Silencing of lncRNA MIR497HG via CRISPR/Cas13d Induces Bladder Cancer Progression Through Promoting the Crosstalk Between Hippo/Yap and TGF-β/Smad Signaling

A subset of long non-coding RNAs (lncRNAs), categorized as miRNA-host gene lncRNAs (lnc-miRHGs), is processed to produce miRNAs and involved in cancer progression. This work aimed to investigate the influences and the molecular mechanisms of lnc-miRHGs MIR497HG in bladder cancer (BCa). The miR-497 a...

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Detalles Bibliográficos
Autores principales: Zhuang, Changshui, Liu, Ying, Fu, Shengqiang, Yuan, Chaobo, Luo, Jingwen, Huang, Xueting, Yang, Weifeng, Xie, Wuwei, Zhuang, Chengle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7755977/
https://www.ncbi.nlm.nih.gov/pubmed/33363213
http://dx.doi.org/10.3389/fmolb.2020.616768

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