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Pulmonary mucormycosis masquerading as endobronchial tumour in an immunocompetent pregnant young lady

Pulmonary mucormycosis is a rare but rapidly progressing and life‐threatening fungal infection, usually affecting immunocompromised patients. We report a case of a previously healthy young lady who presented with prolonged cough, weight loss, and haemoptysis. Imaging showed left hilar mass with infi...

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Autores principales: Ng, Khai Lip, Huan, Nai‐Chien, Nasaruddin, Mona Zaria, Muhammad, Noorul Afidza, Daut, Ummi Nadira, Abdul Rahaman, Jamalul Azizi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7756165/
https://www.ncbi.nlm.nih.gov/pubmed/33364028
http://dx.doi.org/10.1002/rcr2.704
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author Ng, Khai Lip
Huan, Nai‐Chien
Nasaruddin, Mona Zaria
Muhammad, Noorul Afidza
Daut, Ummi Nadira
Abdul Rahaman, Jamalul Azizi
author_facet Ng, Khai Lip
Huan, Nai‐Chien
Nasaruddin, Mona Zaria
Muhammad, Noorul Afidza
Daut, Ummi Nadira
Abdul Rahaman, Jamalul Azizi
author_sort Ng, Khai Lip
collection PubMed
description Pulmonary mucormycosis is a rare but rapidly progressing and life‐threatening fungal infection, usually affecting immunocompromised patients. We report a case of a previously healthy young lady who presented with prolonged cough, weight loss, and haemoptysis. Imaging showed left hilar mass with infiltration into the left main bronchus and concurrent mediastinal lymphadenopathy. Flexible bronchoscopy revealed an endobronchial mass occluding the left main bronchus. Tumour debulking was performed using rigid bronchoscopy with cryoprobe and snares. Histopathological examination revealed inflamed tissue with fungal organism. Fungal polymerase chain reaction (PCR) confirmed Rhizopus microsporus. She was treated with two weeks of intravenous amphotericin‐B with complete clinical and radiological resolution.
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spelling pubmed-77561652020-12-23 Pulmonary mucormycosis masquerading as endobronchial tumour in an immunocompetent pregnant young lady Ng, Khai Lip Huan, Nai‐Chien Nasaruddin, Mona Zaria Muhammad, Noorul Afidza Daut, Ummi Nadira Abdul Rahaman, Jamalul Azizi Respirol Case Rep Case Reports Pulmonary mucormycosis is a rare but rapidly progressing and life‐threatening fungal infection, usually affecting immunocompromised patients. We report a case of a previously healthy young lady who presented with prolonged cough, weight loss, and haemoptysis. Imaging showed left hilar mass with infiltration into the left main bronchus and concurrent mediastinal lymphadenopathy. Flexible bronchoscopy revealed an endobronchial mass occluding the left main bronchus. Tumour debulking was performed using rigid bronchoscopy with cryoprobe and snares. Histopathological examination revealed inflamed tissue with fungal organism. Fungal polymerase chain reaction (PCR) confirmed Rhizopus microsporus. She was treated with two weeks of intravenous amphotericin‐B with complete clinical and radiological resolution. John Wiley & Sons, Ltd 2020-12-23 /pmc/articles/PMC7756165/ /pubmed/33364028 http://dx.doi.org/10.1002/rcr2.704 Text en © 2020 The Authors. Respirology Case Reports published by John Wiley & Sons Australia, Ltd on behalf of The Asian Pacific Society of Respirology This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Reports
Ng, Khai Lip
Huan, Nai‐Chien
Nasaruddin, Mona Zaria
Muhammad, Noorul Afidza
Daut, Ummi Nadira
Abdul Rahaman, Jamalul Azizi
Pulmonary mucormycosis masquerading as endobronchial tumour in an immunocompetent pregnant young lady
title Pulmonary mucormycosis masquerading as endobronchial tumour in an immunocompetent pregnant young lady
title_full Pulmonary mucormycosis masquerading as endobronchial tumour in an immunocompetent pregnant young lady
title_fullStr Pulmonary mucormycosis masquerading as endobronchial tumour in an immunocompetent pregnant young lady
title_full_unstemmed Pulmonary mucormycosis masquerading as endobronchial tumour in an immunocompetent pregnant young lady
title_short Pulmonary mucormycosis masquerading as endobronchial tumour in an immunocompetent pregnant young lady
title_sort pulmonary mucormycosis masquerading as endobronchial tumour in an immunocompetent pregnant young lady
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7756165/
https://www.ncbi.nlm.nih.gov/pubmed/33364028
http://dx.doi.org/10.1002/rcr2.704
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