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Sarcoidosis presenting as vocal cord palsy: an unusual presentation and literature review

We report the case of a 60‐year‐old woman, presenting with left vocal cord paralysis (VCP). Diagnostic evaluation revealed sarcoidosis to be the underlying pathology. Computed tomography (CT) scans exhibited enlarged subcarinal, pretracheal, and prevascular lymph nodes as the possible mechanism of l...

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Autores principales: Raja, Mohummad Hassan Raza, Javed, Muhammad Abdullah, Zubairi, Ali Bin Sarwar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7756166/
https://www.ncbi.nlm.nih.gov/pubmed/33364029
http://dx.doi.org/10.1002/rcr2.705
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author Raja, Mohummad Hassan Raza
Javed, Muhammad Abdullah
Zubairi, Ali Bin Sarwar
author_facet Raja, Mohummad Hassan Raza
Javed, Muhammad Abdullah
Zubairi, Ali Bin Sarwar
author_sort Raja, Mohummad Hassan Raza
collection PubMed
description We report the case of a 60‐year‐old woman, presenting with left vocal cord paralysis (VCP). Diagnostic evaluation revealed sarcoidosis to be the underlying pathology. Computed tomography (CT) scans exhibited enlarged subcarinal, pretracheal, and prevascular lymph nodes as the possible mechanism of left VCP through compression of the left recurrent laryngeal nerve. Initial treatment with oral prednisolone and azathioprine led to remission of symptoms; however, tapering of dosage led to relapse of cough without any signs of VCP. The dosage of prednisolone was further boosted, leading to complete remission. A review of literature reveals 20 cases have been reported to date, with all but one involving the left vocal cord. This is the first reported case, with a relapse of the disease without a relapse of VCP, indicating the rarity of sarcoidosis‐associated VCP.
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spelling pubmed-77561662020-12-23 Sarcoidosis presenting as vocal cord palsy: an unusual presentation and literature review Raja, Mohummad Hassan Raza Javed, Muhammad Abdullah Zubairi, Ali Bin Sarwar Respirol Case Rep Case Reports We report the case of a 60‐year‐old woman, presenting with left vocal cord paralysis (VCP). Diagnostic evaluation revealed sarcoidosis to be the underlying pathology. Computed tomography (CT) scans exhibited enlarged subcarinal, pretracheal, and prevascular lymph nodes as the possible mechanism of left VCP through compression of the left recurrent laryngeal nerve. Initial treatment with oral prednisolone and azathioprine led to remission of symptoms; however, tapering of dosage led to relapse of cough without any signs of VCP. The dosage of prednisolone was further boosted, leading to complete remission. A review of literature reveals 20 cases have been reported to date, with all but one involving the left vocal cord. This is the first reported case, with a relapse of the disease without a relapse of VCP, indicating the rarity of sarcoidosis‐associated VCP. John Wiley & Sons, Ltd 2020-12-23 /pmc/articles/PMC7756166/ /pubmed/33364029 http://dx.doi.org/10.1002/rcr2.705 Text en © 2020 The Authors. Respirology Case Reports published by John Wiley & Sons Australia, Ltd on behalf of The Asian Pacific Society of Respirology This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Reports
Raja, Mohummad Hassan Raza
Javed, Muhammad Abdullah
Zubairi, Ali Bin Sarwar
Sarcoidosis presenting as vocal cord palsy: an unusual presentation and literature review
title Sarcoidosis presenting as vocal cord palsy: an unusual presentation and literature review
title_full Sarcoidosis presenting as vocal cord palsy: an unusual presentation and literature review
title_fullStr Sarcoidosis presenting as vocal cord palsy: an unusual presentation and literature review
title_full_unstemmed Sarcoidosis presenting as vocal cord palsy: an unusual presentation and literature review
title_short Sarcoidosis presenting as vocal cord palsy: an unusual presentation and literature review
title_sort sarcoidosis presenting as vocal cord palsy: an unusual presentation and literature review
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7756166/
https://www.ncbi.nlm.nih.gov/pubmed/33364029
http://dx.doi.org/10.1002/rcr2.705
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