Upregulated LRRC55 promotes BK channel activation and aggravates cell injury in podocytes

Podocyte injury is a common hallmark in various glomerular diseases. The level of LRRC55 was increased in podocytes of patients with focal segmental glomerulosclerosis (FSGS), diabetic nephropathy (DN), and membranous nephropathy (MN). Upregulated LRRC55 and increased intracellular Ca(2+) led to BK...

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Detalles Bibliográficos
Autores principales: Hu, Shuai, Han, Runhong, Chen, Long, Qin, Weisong, Xu, Xiaodong, Shi, Jingsong, Zhu, Xiaodong, Zhang, Mingchao, Zeng, Caihong, Tang, Zheng, Bao, Hao, Liu, Zhihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
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Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7756252/
https://www.ncbi.nlm.nih.gov/pubmed/33346797
http://dx.doi.org/10.1084/jem.20192373

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