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Targeted Protein Degradation as a Promising Tool for Epigenetic Upregulation of Fetal Hemoglobin
The level of fetal hemoglobin (HbF) is an important disease modifier for β‐thalassemia and sickle cell disease patients. Indeed, genetic tinkering with the HbF repression machinery has demonstrated great potential for disease mitigation. Such genetic treatments are costly and the high incidence of β...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7756256/ https://www.ncbi.nlm.nih.gov/pubmed/33002296 http://dx.doi.org/10.1002/cmdc.202000574 |