Reaction Pathways and Redox States in α‐Selective Cobalt‐Catalyzed Hydroborations of Alkynes

Cobalt(II) alkyl complexes supported by a monoanionic NNN pincer ligand are pre‐catalysts for the regioselective hydroboration of terminal alkynes, yielding the Markovnikov products with α:β‐(E) ratios of up to 97:3. A cobalt(II) hydride and a cobalt(II) vinyl complex appear to determine the main re...

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Autores principales: Blasius, Clemens K., Vasilenko, Vladislav, Matveeva, Regina, Wadepohl, Hubert, Gade, Lutz H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7756293/
https://www.ncbi.nlm.nih.gov/pubmed/32889757
http://dx.doi.org/10.1002/anie.202009625
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author Blasius, Clemens K.
Vasilenko, Vladislav
Matveeva, Regina
Wadepohl, Hubert
Gade, Lutz H.
author_facet Blasius, Clemens K.
Vasilenko, Vladislav
Matveeva, Regina
Wadepohl, Hubert
Gade, Lutz H.
author_sort Blasius, Clemens K.
collection PubMed
description Cobalt(II) alkyl complexes supported by a monoanionic NNN pincer ligand are pre‐catalysts for the regioselective hydroboration of terminal alkynes, yielding the Markovnikov products with α:β‐(E) ratios of up to 97:3. A cobalt(II) hydride and a cobalt(II) vinyl complex appear to determine the main reaction pathway. In a background reaction the highly reactive hydrido species specifically converts to a coordinatively unsaturated cobalt(I) complex which was found to re‐enter the main catalytic cycle.
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spelling pubmed-77562932020-12-28 Reaction Pathways and Redox States in α‐Selective Cobalt‐Catalyzed Hydroborations of Alkynes Blasius, Clemens K. Vasilenko, Vladislav Matveeva, Regina Wadepohl, Hubert Gade, Lutz H. Angew Chem Int Ed Engl Communications Cobalt(II) alkyl complexes supported by a monoanionic NNN pincer ligand are pre‐catalysts for the regioselective hydroboration of terminal alkynes, yielding the Markovnikov products with α:β‐(E) ratios of up to 97:3. A cobalt(II) hydride and a cobalt(II) vinyl complex appear to determine the main reaction pathway. In a background reaction the highly reactive hydrido species specifically converts to a coordinatively unsaturated cobalt(I) complex which was found to re‐enter the main catalytic cycle. John Wiley and Sons Inc. 2020-10-15 2020-12-14 /pmc/articles/PMC7756293/ /pubmed/32889757 http://dx.doi.org/10.1002/anie.202009625 Text en © 2020 The Authors. Published by Wiley-VCH GmbH This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Communications
Blasius, Clemens K.
Vasilenko, Vladislav
Matveeva, Regina
Wadepohl, Hubert
Gade, Lutz H.
Reaction Pathways and Redox States in α‐Selective Cobalt‐Catalyzed Hydroborations of Alkynes
title Reaction Pathways and Redox States in α‐Selective Cobalt‐Catalyzed Hydroborations of Alkynes
title_full Reaction Pathways and Redox States in α‐Selective Cobalt‐Catalyzed Hydroborations of Alkynes
title_fullStr Reaction Pathways and Redox States in α‐Selective Cobalt‐Catalyzed Hydroborations of Alkynes
title_full_unstemmed Reaction Pathways and Redox States in α‐Selective Cobalt‐Catalyzed Hydroborations of Alkynes
title_short Reaction Pathways and Redox States in α‐Selective Cobalt‐Catalyzed Hydroborations of Alkynes
title_sort reaction pathways and redox states in α‐selective cobalt‐catalyzed hydroborations of alkynes
topic Communications
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7756293/
https://www.ncbi.nlm.nih.gov/pubmed/32889757
http://dx.doi.org/10.1002/anie.202009625
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AT wadepohlhubert reactionpathwaysandredoxstatesinaselectivecobaltcatalyzedhydroborationsofalkynes
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