Exosomal microRNA‐139‐5p from mesenchymal stem cells accelerates trophoblast cell invasion and migration by motivation of the ERK/MMP‐2 pathway via downregulation of protein tyrosine phosphatase

AIM: Exosomes present essential roles for intercellular interaction via extracellular pathways during systemic dysfunctions, including preeclampsia (PE). Here, we assessed the specific mechanism of mesenchymal stem cells (MSC)‐originated exosomes in PE. METHODS: The effects of exosomes on trophoblas...

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Detalles Bibliográficos
Autores principales: Liu, Huijie, Wang, Fang, Zhang, Ying, Xing, Yanling, Wang, Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Australia, Ltd 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7756315/
https://www.ncbi.nlm.nih.gov/pubmed/32945060
http://dx.doi.org/10.1111/jog.14495

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