Design of a Multiuse Photoreactor To Enable Visible‐Light Photocatalytic Chemical Transformations and Labeling in Live Cells

Despite the growing use of visible‐light photochemistry in both chemistry and biology, no general low‐heat photoreactor for use across these different disciplines exists. Herein, we describe the design and use of a standardized photoreactor for visible‐light‐driven activation and photocatalytic chemical transformations. Using this single benchtop photoreactor, we performed photoredox reactions across multiple visible light wavelengths, a high‐throughput photocatalytic cross‐coupling reaction, and in vitro labeling of proteins and live cells. Given the success of this reactor in all tested applications, we envision that this multi‐use photoreactor will be widely used in biology, chemical biology, and medicinal chemistry settings.