Impact of Physiologically Based Pharmacokinetics, Population Pharmacokinetics and Pharmacokinetics/Pharmacodynamics in the Development of Antibody‐Drug Conjugates

Antibody‐drug conjugates are important molecular entities in the treatment of cancer, with 8 antibody‐drug conjugates approved by the US Food and Drug Administration since 2000 and many more in early‐ and late‐stage clinical development. These conjugates combine the target specificity of monoclonal...

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Detalles Bibliográficos
Autores principales: Li, Chunze, Chen, Shang‐Chiung, Chen, Yuan, Girish, Sandhya, Kågedal, Matts, Lu, Dan, Lu, Tong, Samineni, Divya, Jin, Jin Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Supplement Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7756373/
https://www.ncbi.nlm.nih.gov/pubmed/33205423
http://dx.doi.org/10.1002/jcph.1720

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