Serial Femtosecond Zero Dose Crystallography Captures a Water‐Free Distal Heme Site in a Dye‐Decolorising Peroxidase to Reveal a Catalytic Role for an Arginine in Fe(IV)=O Formation

Obtaining structures of intact redox states of metal centers derived from zero dose X‐ray crystallography can advance our mechanistic understanding of metalloenzymes. In dye‐decolorising heme peroxidases (DyPs), controversy exists regarding the mechanistic role of the distal heme residues aspartate...

Descripción completa

Detalles Bibliográficos
Autores principales: Lučić, Marina, Svistunenko, Dimitri A., Wilson, Michael T., Chaplin, Amanda K., Davy, Bradley, Ebrahim, Ali, Axford, Danny, Tosha, Takehiko, Sugimoto, Hiroshi, Owada, Shigeki, Dworkowski, Florian S. N., Tews, Ivo, Owen, Robin L., Hough, Michael A., Worrall, Jonathan A. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7756461/
https://www.ncbi.nlm.nih.gov/pubmed/32780931
http://dx.doi.org/10.1002/anie.202008622

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7756461/
https://www.ncbi.nlm.nih.gov/pubmed/32780931
http://dx.doi.org/10.1002/anie.202008622

Ejemplares similares