Picky ABCG5/G8 and promiscuous ABCG2 ‐ a tale of fatty diets and drug toxicity

Structural data on ABCG5/G8 and ABCG2 reveal a unique molecular architecture for subfamily G ATP‐binding cassette (ABCG) transporters and disclose putative substrate‐binding sites. ABCG5/G8 and ABCG2 appear to use several unique structural motifs to execute transport, including the triple helical bu...

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Detalles Bibliográficos
Autores principales: Khunweeraphong, Narakorn, Mitchell‐White, James, Szöllősi, Dániel, Hussein, Toka, Kuchler, Karl, Kerr, Ian D., Stockner, Thomas, Lee, Jyh‐Yeuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Review Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7756502/
https://www.ncbi.nlm.nih.gov/pubmed/32978801
http://dx.doi.org/10.1002/1873-3468.13938

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7756502/
https://www.ncbi.nlm.nih.gov/pubmed/32978801
http://dx.doi.org/10.1002/1873-3468.13938

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