Insights into Ruthenium(II/IV)‐Catalyzed Distal C−H Oxygenation by Weak Coordination

C−H hydroxylation of aryl acetamides and alkyl phenylacetyl esters was accomplished via challenging distal weak O‐coordination by versatile ruthenium(II/IV) catalysis. The ruthenium(II)‐catalyzed C−H oxygenation of aryl acetamides proceeded through C−H activation, ruthenium(II/IV) oxidation and redu...

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Autores principales: Bu, Qingqing, Kuniyil, Rositha, Shen, Zhigao, Gońka, Elżbieta, Ackermann, Lutz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7756554/
https://www.ncbi.nlm.nih.gov/pubmed/32596872
http://dx.doi.org/10.1002/chem.202003062
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author Bu, Qingqing
Kuniyil, Rositha
Shen, Zhigao
Gońka, Elżbieta
Ackermann, Lutz
author_facet Bu, Qingqing
Kuniyil, Rositha
Shen, Zhigao
Gońka, Elżbieta
Ackermann, Lutz
author_sort Bu, Qingqing
collection PubMed
description C−H hydroxylation of aryl acetamides and alkyl phenylacetyl esters was accomplished via challenging distal weak O‐coordination by versatile ruthenium(II/IV) catalysis. The ruthenium(II)‐catalyzed C−H oxygenation of aryl acetamides proceeded through C−H activation, ruthenium(II/IV) oxidation and reductive elimination, thus providing step‐economical access to valuable phenols. The p‐cymene‐ruthenium(II/IV) manifold was established by detailed experimental and DFT‐computational studies.
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spelling pubmed-77565542020-12-28 Insights into Ruthenium(II/IV)‐Catalyzed Distal C−H Oxygenation by Weak Coordination Bu, Qingqing Kuniyil, Rositha Shen, Zhigao Gońka, Elżbieta Ackermann, Lutz Chemistry Full Papers C−H hydroxylation of aryl acetamides and alkyl phenylacetyl esters was accomplished via challenging distal weak O‐coordination by versatile ruthenium(II/IV) catalysis. The ruthenium(II)‐catalyzed C−H oxygenation of aryl acetamides proceeded through C−H activation, ruthenium(II/IV) oxidation and reductive elimination, thus providing step‐economical access to valuable phenols. The p‐cymene‐ruthenium(II/IV) manifold was established by detailed experimental and DFT‐computational studies. John Wiley and Sons Inc. 2020-10-29 2020-12-09 /pmc/articles/PMC7756554/ /pubmed/32596872 http://dx.doi.org/10.1002/chem.202003062 Text en © 2020 The Authors. Published by Wiley-VCH GmbH This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Full Papers
Bu, Qingqing
Kuniyil, Rositha
Shen, Zhigao
Gońka, Elżbieta
Ackermann, Lutz
Insights into Ruthenium(II/IV)‐Catalyzed Distal C−H Oxygenation by Weak Coordination
title Insights into Ruthenium(II/IV)‐Catalyzed Distal C−H Oxygenation by Weak Coordination
title_full Insights into Ruthenium(II/IV)‐Catalyzed Distal C−H Oxygenation by Weak Coordination
title_fullStr Insights into Ruthenium(II/IV)‐Catalyzed Distal C−H Oxygenation by Weak Coordination
title_full_unstemmed Insights into Ruthenium(II/IV)‐Catalyzed Distal C−H Oxygenation by Weak Coordination
title_short Insights into Ruthenium(II/IV)‐Catalyzed Distal C−H Oxygenation by Weak Coordination
title_sort insights into ruthenium(ii/iv)‐catalyzed distal c−h oxygenation by weak coordination
topic Full Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7756554/
https://www.ncbi.nlm.nih.gov/pubmed/32596872
http://dx.doi.org/10.1002/chem.202003062
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