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Enteropeptidase inhibition improves kidney function in a rat model of diabetic kidney disease

AIM: To examine the effects of an enteropeptidase inhibitor, SCO‐792, on kidney function in rats. MATERIALS AND METHODS: The pharmacological effects of SCO‐792 were evaluated in Wistar fatty (WF) rats, a rat model of diabetic kidney disease (DKD). RESULTS: Oral administration of SCO‐792 increased fa...

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Detalles Bibliográficos
Autores principales: Sugama, Jun, Katayama, Yuko, Moritoh, Yusuke, Watanabe, Masanori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7756647/
https://www.ncbi.nlm.nih.gov/pubmed/32893449
http://dx.doi.org/10.1111/dom.14190