Hepatitis B core‐related antigen levels predict recurrence‐free survival in patients with HBV‐associated early‐stage hepatocellular carcinoma: results from a Dutch long‐term follow‐up study

Prognosis of hepatitis B (HBV)‐associated hepatocellular carcinoma (HCC) is poor due to high rates of HCC recurrence and progression of underlying liver disease. We studied whether serum hepatitis B core‐related antigen (HBcrAg) levels could predict HCC recurrence and outcome in HBV associated. High...

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Autores principales: Beudeker, Boris J. B., Groothuismink, Zwier M. A., de Man, Robert A., Witjes, Caroline D. M., van der Eijk, Annemiek A., Boonstra, Andre, Sonneveld, Milan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7756674/
https://www.ncbi.nlm.nih.gov/pubmed/32869922
http://dx.doi.org/10.1111/jvh.13394
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author Beudeker, Boris J. B.
Groothuismink, Zwier M. A.
de Man, Robert A.
Witjes, Caroline D. M.
van der Eijk, Annemiek A.
Boonstra, Andre
Sonneveld, Milan J.
author_facet Beudeker, Boris J. B.
Groothuismink, Zwier M. A.
de Man, Robert A.
Witjes, Caroline D. M.
van der Eijk, Annemiek A.
Boonstra, Andre
Sonneveld, Milan J.
author_sort Beudeker, Boris J. B.
collection PubMed
description Prognosis of hepatitis B (HBV)‐associated hepatocellular carcinoma (HCC) is poor due to high rates of HCC recurrence and progression of underlying liver disease. We studied whether serum hepatitis B core‐related antigen (HBcrAg) levels could predict HCC recurrence and outcome in HBV associated. Higher HBcrAg levels at HCC diagnosis were independently associated with reduced overall and recurrence‐free survival in patients with early, but not advanced, stage HCC.
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spelling pubmed-77566742020-12-28 Hepatitis B core‐related antigen levels predict recurrence‐free survival in patients with HBV‐associated early‐stage hepatocellular carcinoma: results from a Dutch long‐term follow‐up study Beudeker, Boris J. B. Groothuismink, Zwier M. A. de Man, Robert A. Witjes, Caroline D. M. van der Eijk, Annemiek A. Boonstra, Andre Sonneveld, Milan J. J Viral Hepat Short Communication Prognosis of hepatitis B (HBV)‐associated hepatocellular carcinoma (HCC) is poor due to high rates of HCC recurrence and progression of underlying liver disease. We studied whether serum hepatitis B core‐related antigen (HBcrAg) levels could predict HCC recurrence and outcome in HBV associated. Higher HBcrAg levels at HCC diagnosis were independently associated with reduced overall and recurrence‐free survival in patients with early, but not advanced, stage HCC. John Wiley and Sons Inc. 2020-09-14 2021-01 /pmc/articles/PMC7756674/ /pubmed/32869922 http://dx.doi.org/10.1111/jvh.13394 Text en © 2020 The Authors. Journal of Viral Hepatitis published by John Wiley & Sons Ltd This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Short Communication
Beudeker, Boris J. B.
Groothuismink, Zwier M. A.
de Man, Robert A.
Witjes, Caroline D. M.
van der Eijk, Annemiek A.
Boonstra, Andre
Sonneveld, Milan J.
Hepatitis B core‐related antigen levels predict recurrence‐free survival in patients with HBV‐associated early‐stage hepatocellular carcinoma: results from a Dutch long‐term follow‐up study
title Hepatitis B core‐related antigen levels predict recurrence‐free survival in patients with HBV‐associated early‐stage hepatocellular carcinoma: results from a Dutch long‐term follow‐up study
title_full Hepatitis B core‐related antigen levels predict recurrence‐free survival in patients with HBV‐associated early‐stage hepatocellular carcinoma: results from a Dutch long‐term follow‐up study
title_fullStr Hepatitis B core‐related antigen levels predict recurrence‐free survival in patients with HBV‐associated early‐stage hepatocellular carcinoma: results from a Dutch long‐term follow‐up study
title_full_unstemmed Hepatitis B core‐related antigen levels predict recurrence‐free survival in patients with HBV‐associated early‐stage hepatocellular carcinoma: results from a Dutch long‐term follow‐up study
title_short Hepatitis B core‐related antigen levels predict recurrence‐free survival in patients with HBV‐associated early‐stage hepatocellular carcinoma: results from a Dutch long‐term follow‐up study
title_sort hepatitis b core‐related antigen levels predict recurrence‐free survival in patients with hbv‐associated early‐stage hepatocellular carcinoma: results from a dutch long‐term follow‐up study
topic Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7756674/
https://www.ncbi.nlm.nih.gov/pubmed/32869922
http://dx.doi.org/10.1111/jvh.13394
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