Food‐Poisoning Bacteria Employ a Citrate Synthase and a Type II NRPS To Synthesize Bolaamphiphilic Lipopeptide Antibiotics

Mining the genome of the food‐spoiling bacterium Burkholderia gladioli pv. cocovenenans revealed five nonribosomal peptide synthetase (NRPS) gene clusters, including an orphan gene locus (bol). Gene inactivation and metabolic profiling linked the bol gene cluster to novel bolaamphiphilic lipopeptide...

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Detalles Bibliográficos
Autores principales: Dose, Benjamin, Ross, Claudia, Niehs, Sarah P., Scherlach, Kirstin, Bauer, Johanna P., Hertweck, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7756705/
https://www.ncbi.nlm.nih.gov/pubmed/32780428
http://dx.doi.org/10.1002/anie.202009107

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7756705/
https://www.ncbi.nlm.nih.gov/pubmed/32780428
http://dx.doi.org/10.1002/anie.202009107

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