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Beating cancer‐related fatigue with the Untire mobile app: Results from a waiting‐list randomized controlled trial

OBJECTIVE: This waiting‐list randomized controlled trial examined the effectiveness of a self‐management mHealth app in improving fatigue and quality of life (QoL) in cancer patients and survivors. METHODS: Persons with cancer‐related fatigue (CRF) were recruited across four English speaking countri...

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Autores principales: Spahrkäs, Simon Sebastian, Looijmans, Anne, Sanderman, Robbert, Hagedoorn, Mariët
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7756868/
https://www.ncbi.nlm.nih.gov/pubmed/33393199
http://dx.doi.org/10.1002/pon.5492
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author Spahrkäs, Simon Sebastian
Looijmans, Anne
Sanderman, Robbert
Hagedoorn, Mariët
author_facet Spahrkäs, Simon Sebastian
Looijmans, Anne
Sanderman, Robbert
Hagedoorn, Mariët
author_sort Spahrkäs, Simon Sebastian
collection PubMed
description OBJECTIVE: This waiting‐list randomized controlled trial examined the effectiveness of a self‐management mHealth app in improving fatigue and quality of life (QoL) in cancer patients and survivors. METHODS: Persons with cancer‐related fatigue (CRF) were recruited across four English speaking countries, via social media, and randomized into intervention (n = 519) and control (n = 280) groups. Whereas the intervention group received immediate access to the Untire app, the control group received access only after 12‐weeks. Primary outcomes fatigue severity and interference, and secondary outcome QoL were assessed at baseline, 4, 8, and 12‐weeks. We ran generalized linear mixed models for all outcomes to determine the effects of app access (yes/no), over 12‐weeks, following the intention‐to‐treat principle. RESULTS: Compared with the control group, the intervention group showed significantly larger improvements in fatigue severity (d = 0.40), fatigue interference (d = 0.35), and overall QoL on average (d = 0.32) (P's < .01), but not for overall QoL in the past week (P = .07). Sensitivity analyses indicated that participants with medium or high app use benefited most when compared with nonusers and control participants (P's ≤ .02). The intervention effect on fatigue interference was slightly stronger in younger participants (≤56 vs. >56). Effects did not depend on education and cancer status. Reliable change analyses indicated that significantly more people showed full recovery for fatigue in the intervention vs the control group (P's = .02). CONCLUSIONS: The Untire app can be an effective mHealth solution for cancer patients and survivors with moderate to severe CRF.
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spelling pubmed-77568682020-12-28 Beating cancer‐related fatigue with the Untire mobile app: Results from a waiting‐list randomized controlled trial Spahrkäs, Simon Sebastian Looijmans, Anne Sanderman, Robbert Hagedoorn, Mariët Psychooncology Papers OBJECTIVE: This waiting‐list randomized controlled trial examined the effectiveness of a self‐management mHealth app in improving fatigue and quality of life (QoL) in cancer patients and survivors. METHODS: Persons with cancer‐related fatigue (CRF) were recruited across four English speaking countries, via social media, and randomized into intervention (n = 519) and control (n = 280) groups. Whereas the intervention group received immediate access to the Untire app, the control group received access only after 12‐weeks. Primary outcomes fatigue severity and interference, and secondary outcome QoL were assessed at baseline, 4, 8, and 12‐weeks. We ran generalized linear mixed models for all outcomes to determine the effects of app access (yes/no), over 12‐weeks, following the intention‐to‐treat principle. RESULTS: Compared with the control group, the intervention group showed significantly larger improvements in fatigue severity (d = 0.40), fatigue interference (d = 0.35), and overall QoL on average (d = 0.32) (P's < .01), but not for overall QoL in the past week (P = .07). Sensitivity analyses indicated that participants with medium or high app use benefited most when compared with nonusers and control participants (P's ≤ .02). The intervention effect on fatigue interference was slightly stronger in younger participants (≤56 vs. >56). Effects did not depend on education and cancer status. Reliable change analyses indicated that significantly more people showed full recovery for fatigue in the intervention vs the control group (P's = .02). CONCLUSIONS: The Untire app can be an effective mHealth solution for cancer patients and survivors with moderate to severe CRF. John Wiley and Sons Inc. 2020-10-11 2020-11 /pmc/articles/PMC7756868/ /pubmed/33393199 http://dx.doi.org/10.1002/pon.5492 Text en © 2020 The Authors. Psycho‐Oncology published by John Wiley & Sons Ltd. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Papers
Spahrkäs, Simon Sebastian
Looijmans, Anne
Sanderman, Robbert
Hagedoorn, Mariët
Beating cancer‐related fatigue with the Untire mobile app: Results from a waiting‐list randomized controlled trial
title Beating cancer‐related fatigue with the Untire mobile app: Results from a waiting‐list randomized controlled trial
title_full Beating cancer‐related fatigue with the Untire mobile app: Results from a waiting‐list randomized controlled trial
title_fullStr Beating cancer‐related fatigue with the Untire mobile app: Results from a waiting‐list randomized controlled trial
title_full_unstemmed Beating cancer‐related fatigue with the Untire mobile app: Results from a waiting‐list randomized controlled trial
title_short Beating cancer‐related fatigue with the Untire mobile app: Results from a waiting‐list randomized controlled trial
title_sort beating cancer‐related fatigue with the untire mobile app: results from a waiting‐list randomized controlled trial
topic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7756868/
https://www.ncbi.nlm.nih.gov/pubmed/33393199
http://dx.doi.org/10.1002/pon.5492
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