Cargando…
Acute lymphoblastic leukaemia (ALL) things come to those who wait: 60 years of progress in the treatment of adult ALL
The UK has made a well‐recognised contribution to the international effort to understand and treat acute lymphoblastic leukaemia (ALL) in adults. Work done in the UK by numerous personnel over many years has been instrumental in developing novel risk stratifications, evaluating treatment strategies...
Autores principales: | , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7756887/ https://www.ncbi.nlm.nih.gov/pubmed/33190258 http://dx.doi.org/10.1111/bjh.17166 |
_version_ | 1783626640946888704 |
---|---|
author | Fielding, Adele K. Goldstone, Anthony H. |
author_facet | Fielding, Adele K. Goldstone, Anthony H. |
author_sort | Fielding, Adele K. |
collection | PubMed |
description | The UK has made a well‐recognised contribution to the international effort to understand and treat acute lymphoblastic leukaemia (ALL) in adults. Work done in the UK by numerous personnel over many years has been instrumental in developing novel risk stratifications, evaluating treatment strategies for adult patients with de novo and relapsed disease and in making novel scientific contributions. The UK has championed and achieved very high levels of recruitment to clinical trials and, in particular, is known for success in large, investigator‐initiated randomised controlled trials. This historical review charts the progress of clinical research in adult ALL from its inception to the present day. |
format | Online Article Text |
id | pubmed-7756887 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-77568872020-12-28 Acute lymphoblastic leukaemia (ALL) things come to those who wait: 60 years of progress in the treatment of adult ALL Fielding, Adele K. Goldstone, Anthony H. Br J Haematol British Society For Haematology 60th Anniversary Special Issue The UK has made a well‐recognised contribution to the international effort to understand and treat acute lymphoblastic leukaemia (ALL) in adults. Work done in the UK by numerous personnel over many years has been instrumental in developing novel risk stratifications, evaluating treatment strategies for adult patients with de novo and relapsed disease and in making novel scientific contributions. The UK has championed and achieved very high levels of recruitment to clinical trials and, in particular, is known for success in large, investigator‐initiated randomised controlled trials. This historical review charts the progress of clinical research in adult ALL from its inception to the present day. John Wiley and Sons Inc. 2020-11-15 2020-11 /pmc/articles/PMC7756887/ /pubmed/33190258 http://dx.doi.org/10.1111/bjh.17166 Text en © 2020 The Authors. British Journal of Haematology published by British Society for Haematology and John Wiley & Sons Ltd. This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made. |
spellingShingle | British Society For Haematology 60th Anniversary Special Issue Fielding, Adele K. Goldstone, Anthony H. Acute lymphoblastic leukaemia (ALL) things come to those who wait: 60 years of progress in the treatment of adult ALL |
title | Acute lymphoblastic leukaemia (ALL) things come to those who wait: 60 years of progress in the treatment of adult ALL |
title_full | Acute lymphoblastic leukaemia (ALL) things come to those who wait: 60 years of progress in the treatment of adult ALL |
title_fullStr | Acute lymphoblastic leukaemia (ALL) things come to those who wait: 60 years of progress in the treatment of adult ALL |
title_full_unstemmed | Acute lymphoblastic leukaemia (ALL) things come to those who wait: 60 years of progress in the treatment of adult ALL |
title_short | Acute lymphoblastic leukaemia (ALL) things come to those who wait: 60 years of progress in the treatment of adult ALL |
title_sort | acute lymphoblastic leukaemia (all) things come to those who wait: 60 years of progress in the treatment of adult all |
topic | British Society For Haematology 60th Anniversary Special Issue |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7756887/ https://www.ncbi.nlm.nih.gov/pubmed/33190258 http://dx.doi.org/10.1111/bjh.17166 |
work_keys_str_mv | AT fieldingadelek acutelymphoblasticleukaemiaallthingscometothosewhowait60yearsofprogressinthetreatmentofadultall AT goldstoneanthonyh acutelymphoblasticleukaemiaallthingscometothosewhowait60yearsofprogressinthetreatmentofadultall |