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Germline variation of Ribonuclease H2 genes in ovarian cancer patients

Epithelial ovarian carcinoma (EOC) is a genetically heterogeneous disease that is partly driven by molecular defects in mismatch repair (MMR) or homology-directed DNA repair (HDR). Ribonuclease H2 serves to remove mis-incorporated ribonucleotides from DNA which alleviates HDR mechanisms and guides t...

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Detalles Bibliográficos
Autores principales:	Polaczek, Rahel, Schürmann, Peter, Speith, Lisa-Marie, Geffers, Robert, Dürst, Matthias, Hillemanns, Peter, Park-Simon, Tjoung-Won, Liebrich, Clemens, Dörk, Thilo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Brief Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7756920/ https://www.ncbi.nlm.nih.gov/pubmed/33353557 http://dx.doi.org/10.1186/s13048-020-00753-1

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