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CAFs affect the proliferation and treatment response of head and neck cancer spheroids during co-culturing in a unique in vitro model
BACKGROUND: Head and neck squamous cell carcinoma (HNSCC) is a heterogeneous group of tumors for which the overall survival rate worldwide is around 60%. The tumor microenvironment, including cancer-associated fibroblasts (CAFs), is believed to affect the treatment response and migration of HNSCC. T...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7756959/ https://www.ncbi.nlm.nih.gov/pubmed/33353547 http://dx.doi.org/10.1186/s12935-020-01718-6 |