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Immunogenic Cell Death of Breast Cancer Stem Cells Induced by an Endoplasmic Reticulum‐Targeting Copper(II) Complex

Immunogenic cell death (ICD) offers a method of stimulating the immune system to attack and remove cancer cells. We report a copper(II) complex containing a Schiff base ligand and a polypyridyl ligand, 4, capable of inducing ICD in breast cancer stem cells (CSCs). Complex 4 kills both bulk breast ca...

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Detalles Bibliográficos
Autores principales: Kaur, Pooja, Johnson, Alice, Northcote‐Smith, Joshua, Lu, Chunxin, Suntharalingam, Kogularamanan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7757018/
https://www.ncbi.nlm.nih.gov/pubmed/32776422
http://dx.doi.org/10.1002/cbic.202000553