Eomesodermin in CD4(+)T cells is essential for Ginkgolide K ameliorating disease progression in experimental autoimmune encephalomyelitis

Eomesodermin (Eomes), a transcription factor, could suppress the Th17 cell differentiation and proliferation through directly binding to the promoter zone of the Rorc and Il17a gene, meanwhile the expression of Eomes is suppressed when c-Jun directly binds to its promoter zone. Ginkgolide K (1,10-di...

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Detalles Bibliográficos
Autores principales: Chen, Sheng, Zhang, Juan, Yu, Wen-Bo, Zhuang, Jing-Cong, Xiao, Wei, Wu, Zhi-Ying, Xiao, Bao-Guo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7757039/
https://www.ncbi.nlm.nih.gov/pubmed/33390832
http://dx.doi.org/10.7150/ijbs.50041

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