Cargando…

Novel Functions of CD147 in the Mitochondria Exacerbates Melanoma Metastasis

Melanoma is an aggressive form of skin cancer characterized by rapid invasion and metastasis. CD147 is known to be functioning in cell invasion. In this study, we showed that CD147 was translocated from the cell membrane to the mitochondria in advanced melanoma. Melanoma patients with CD147 localize...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lu, Lixia, Zhang, Jianglin, Gan, Pingping, Wu, Lisha, Zhang, Xu, peng, Cong, Zhou, Jianda, Chen, Xiang, Su, Juan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2021
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7757041/ https://www.ncbi.nlm.nih.gov/pubmed/33390850 http://dx.doi.org/10.7150/ijbs.52043

Ejemplares similares

Downregulation of CD147 induces malignant melanoma cell apoptosis via the regulation of IGFBP2 expression
por: Zhao, Shuang, et al.
Publicado: (2018)

CD147 silencing inhibits tumor growth by suppressing glucose transport in melanoma
por: Su, Juan, et al.
Publicado: (2016)

TRAF6 regulates EGF-induced cell transformation and cSCC malignant phenotype through CD147/EGFR
por: Zhang, Xu, et al.
Publicado: (2018)

Repressing CD147 is a novel therapeutic strategy for malignant melanoma
por: Hu, Xing, et al.
Publicado: (2017)

Nuclear envelope-distributed CD147 interacts with and inhibits the transcriptional function of RING1 and promotes melanoma cell motility
por: Chen, Junchen, et al.
Publicado: (2017)

A novel chalcone derivative has antitumor activity in melanoma by inducing DNA damage through the upregulation of ROS products
por: Li, Keke, et al.
Publicado: (2020)

TRAF6 regulates melanoma invasion and metastasis through ubiquitination of Basigin
por: Luo, Zhongling, et al.
Publicado: (2016)

Epigallocatechin-3-gallate(EGCG) suppresses melanoma cell growth and metastasis by targeting TRAF6 activity
por: Zhang, Jianglin, et al.
Publicado: (2016)

Epidermal CD147 expression plays a key role in IL-22-induced psoriatic dermatitis
por: Peng, Cong, et al.
Publicado: (2017)

CD147 Promotes Tumor Lymphangiogenesis in Melanoma via PROX-1
por: Reger de Moura, Coralie, et al.
Publicado: (2021)

CD147 mediates epidermal malignant transformation through the RSK2/AP-1 pathway
por: Zhang, Xu, et al.
Publicado: (2022)

Targeting CD147 for T to NK Lineage Reprogramming and Tumor Therapy
por: Geng, Jie-Jie, et al.
Publicado: (2017)

CD147 and matrix-metalloproteinase-2 expression in metastatic and non-metastatic uveal melanomas
por: Lüke, Julia, et al.
Publicado: (2016)

Upregulation of CD147 Promotes Metastasis of Cholangiocarcinoma by Modulating the Epithelial-to-Mesenchymal Transitional Process
por: Dana, Paweena, et al.
Publicado: (2017)

Role of MMP-2 and CD147 in kidney fibrosis
por: Cheng, Zhengyuan, et al.
Publicado: (2022)

In Vitro and In Vivo Prostate Cancer Metastasis and Chemoresistance Can Be Modulated by Expression of either CD44 or CD147
por: Hao, Jingli, et al.
Publicado: (2012)

The Roles of CD147 and/or Cyclophilin A in Kidney Diseases
por: Qu, Xin, et al.
Publicado: (2014)

CD147 blockade as a potential and novel treatment of graft rejection
por: Luan, Jing, et al.
Publicado: (2017)

Interaction of CD147 and human epididymis protein 4 promotes invasion and metastasis of ovarian cancer
por: Gao, Lingling, et al.
Publicado: (2021)

Role of CD147 in the development and diagnosis of hepatocellular carcinoma
por: Huang, Defa, et al.
Publicado: (2023)

Discovery and Biological Evaluation of CD147 N-Glycan Inhibitors: A New Direction in the Treatment of Tumor Metastasis
por: Li, Wenqian, et al.
Publicado: (2020)

Role of melatonin in the treatment of COVID-19; as an adjuvant through cluster differentiation 147 (CD147)
por: Sehirli, Ahmet Ozer, et al.
Publicado: (2020)

Clinical Significance of CD147 in Children with Inflammatory Bowel Disease
por: Wang, Hongli, et al.
Publicado: (2020)

Dealing with the family: CD147 interactions with cyclophilins
por: Yurchenko, Vyacheslav, et al.
Publicado: (2006)

Blockade of Macrophage CD147 Protects Against Foam Cell Formation in Atherosclerosis
por: Lv, Jian-Jun, et al.
Publicado: (2021)

Cuprous oxide nanoparticles inhibit the growth and metastasis of melanoma by targeting mitochondria
por: Wang, Y, et al.
Publicado: (2013)

CD147 expression correlates with lymph node metastasis in T1-T2 squamous cell carcinoma of the tongue
por: Suzuki, Shinsuke, et al.
Publicado: (2017)

CD147 Facilitates the Pathogenesis of Psoriasis through Glycolysis and H3K9me3 Modification in Keratinocytes
por: Chen, Chao, et al.
Publicado: (2023)

Arf6-driven endocytic recycling of CD147 determines HCC malignant phenotypes
por: Qi, Shanshan, et al.
Publicado: (2019)

CD147: an integral and potential molecule to abrogate hallmarks of cancer
por: Nyalali, Alphonce M. K., et al.
Publicado: (2023)

CD147 Mediates 5-Fluorouracil Resistance in Colorectal Cancer by Reprogramming Glycolipid Metabolism
por: Dong, Shuohui, et al.
Publicado: (2022)

The role of CD147 expression in prostate cancer: a systematic review and meta-analysis
por: Ye, Yun, et al.
Publicado: (2016)

CD147 as a Novel Prognostic Biomarker for Hepatocellular Carcinoma: A Meta-Analysis
por: Peng, Fei, et al.
Publicado: (2017)

Novel chloroquine derivative suppresses melanoma cell growth by DNA damage through increasing ROS levels
por: Li, Jiaoduan, et al.
Publicado: (2022)

Wear particles enhance autophagy through up-regulation of CD147 to promote osteoclastogenesis
por: Su, Baohua, et al.
Publicado: (2018)

Active demethylation upregulates CD147 expression promoting non-small cell lung cancer invasion and metastasis
por: Liao, Cheng-Gong, et al.
Publicado: (2022)

CD147 and Prostate Cancer: A Systematic Review and Meta-Analysis
por: Peng, Fei, et al.
Publicado: (2016)

A critical epitope in CD147 facilitates memory CD4(+) T-cell hyper-activation in rheumatoid arthritis
por: Guo, Na, et al.
Publicado: (2018)

CD147 and Cyclooxygenase Expression in Feline Oral Squamous Cell Carcinoma
por: Nasry, Walaa Hamed Shaker, et al.
Publicado: (2018)

N-linked glycosylation at Asn152 on CD147 affects protein folding and stability: promoting tumour metastasis in hepatocellular carcinoma
por: Li, Jiang-Hua, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_bm4c9qrv5g8ebjki445b76kdm3