Cargando…

miRNA-199b-3p suppresses growth and progression of ovarian cancer via the CHK1/E-cadherin/EMT signaling pathway by targeting ZEB1

Ovarian cancer is one of the most common gynecological malignancies and its pathogenesis and progression are regulated by multiple genes. MicroRNAs (miRNAs) are endogenous non-coding RNAs that regulate body function by altering post-transcriptional gene expression. Previous studies have suggested th...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wei, Liqun, He, Yuanqi, Bi, Shuhong, Li, Xiaoxiao, Zhang, Jianzhong, Zhang, Shihong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2021
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7757082/ https://www.ncbi.nlm.nih.gov/pubmed/33416170 http://dx.doi.org/10.3892/or.2020.7895

Ejemplares similares

Inhibiting the redox function of APE1 suppresses cervical cancer metastasis via disengagement of ZEB1 from E-cadherin in EMT
por: Li, Qing, et al.
Publicado: (2021)

The EMT factor ZEB1 paradoxically inhibits EMT in BRAF-mutant carcinomas
por: Sánchez-Tilló, Ester, et al.
Publicado: (2023)

ATM-mediated stabilization of ZEB1 promotes DNA damage response and radioresistance through CHK1
por: Zhang, Peijing, et al.
Publicado: (2014)

An hTERT/ZEB1 complex directly regulates E-cadherin to promote epithelial-to-mesenchymal transition (EMT) in colorectal cancer
por: Qin, Yong, et al.
Publicado: (2015)

The EMT-activator ZEB1 is unrelated to platinum drug resistance in ovarian cancer but is predictive of survival
por: Rae, Sophie, et al.
Publicado: (2022)

Oncogenic functions of the EMT-related transcription factor ZEB1 in breast cancer
por: Wu, Hua-Tao, et al.
Publicado: (2020)

Loss of Key EMT-Regulating miRNAs Highlight the Role of ZEB1 in EGFR Tyrosine Kinase Inhibitor-Resistant NSCLC
por: Gohlke, Linus, et al.
Publicado: (2023)

miR-655 Is an EMT-Suppressive MicroRNA Targeting ZEB1 and TGFBR2
por: Harazono, Yosuke, et al.
Publicado: (2013)

miR-101 suppresses the epithelial-to-mesenchymal transition by targeting ZEB1 and ZEB2 in ovarian carcinoma
por: GUO, FEI, et al.
Publicado: (2014)

PTTG1/ZEB1 Axis Regulates E-Cadherin Expression in Human Seminoma
por: Teveroni, Emanuela, et al.
Publicado: (2022)

Clinical implication of ZEB-1 and E-cadherin expression in hepatocellular carcinoma (HCC)
por: Hashiguchi, Motoyuki, et al.
Publicado: (2013)

ZEB1 Mediates Drug Resistance and EMT in p300-Deficient CRC
por: Lazarova, Darina, et al.
Publicado: (2017)

Chk1, Chk2, is the amplifier on?
por: Dove, Alan W.
Publicado: (2001)

Circular RNA S-7 promotes ovarian cancer EMT via sponging miR-641 to up-regulate ZEB1 and MDM2
por: Zhang, Fenghua, et al.
Publicado: (2020)

NAC1 Regulates Somatic Cell Reprogramming by Controlling Zeb1 and E-cadherin Expression
por: Faiola, Francesco, et al.
Publicado: (2017)

Clinicopathological significance of ZEB-1 and E-cadherin proteins in patients with oral cavity squamous cell carcinoma
por: Yao, Xiaofeng, et al.
Publicado: (2017)

Prognostic significance of E-cadherin and ZEB1 expression in intraductal papillary mucinous neoplasm
por: Chang, Ye Rim, et al.
Publicado: (2017)

ELF3 is an antagonist of oncogenic-signalling-induced expression of EMT-TF ZEB1
por: Liu, D, et al.
Publicado: (2018)

EMT transcription factor ZEB1 alters the epigenetic landscape of colorectal cancer cells
por: Lindner, Pablo, et al.
Publicado: (2020)

Chk1 suppressed cell death
por: Meuth, Mark
Publicado: (2010)

LncRNA PLAC2 Positively Regulates CDK2 to Promote Ovarian Carcinoma Cell Proliferation
por: He, Yuanqi, et al.
Publicado: (2020)

Resistance to the CHK1 inhibitor prexasertib involves functionally distinct CHK1 activities in BRCA wild-type ovarian cancer
por: Nair, Jayakumar, et al.
Publicado: (2020)

Comparison of Snail1, ZEB1, E-Cadherin Expression Levels in HPV-Induced Cervical Cancer
por: FARZANEHPOUR, Mahdieh, et al.
Publicado: (2020)

Genome‐wide cooperation of EMT transcription factor ZEB1 with YAP and AP‐1 in breast cancer
por: Feldker, Nora, et al.
Publicado: (2020)

Sip1 mediates an E-cadherin-to-N-cadherin switch during cranial neural crest EMT
por: Rogers, Crystal D., et al.
Publicado: (2013)

Prognostic Role of Epithelial-Mesenchymal Transition Markers “E-Cadherin, β-Catenin, ZEB1, ZEB2 and p63” in Bladder Carcinoma
por: Moussa, Rabab Ahmed, et al.
Publicado: (2019)

Interplay between the EMT transcription factors ZEB1 and ZEB2 regulates hematopoietic stem and progenitor cell differentiation and hematopoietic lineage fidelity
por: Wang, Jueqiong, et al.
Publicado: (2021)

ZEB1-induced LINC01559 expedites cell proliferation, migration and EMT process in gastric cancer through recruiting IGF2BP2 to stabilize ZEB1 expression
por: Shen, Huojian, et al.
Publicado: (2021)

The EMT-activator ZEB1 induces bone metastasis associated genes including BMP-inhibitors
por: Mock, Kerstin, et al.
Publicado: (2015)

E-Cadherin Is Transcriptionally Activated via Suppression of ZEB1 Transcriptional Repressor by Small RNA-Mediated Gene Silencing
por: Mazda, Minami, et al.
Publicado: (2011)

Inhibition of CHK1 enhances cell death induced by the Bcl-2-selective inhibitor ABT-199 in acute myeloid leukemia cells
por: Zhao, Jianyun, et al.
Publicado: (2016)

Radiation induces NORAD expression to promote ESCC radiotherapy resistance via EEPD1/ATR/Chk1 signalling and by inhibiting pri-miR-199a1 processing and the exosomal transfer of miR-199a-5p
por: Sun, Yuchen, et al.
Publicado: (2021)

miRNA-641 inhibits the proliferation, migration, and invasion and induces apoptosis of cervical cancer cells by directly targeting ZEB1
por: Yao, Rui, et al.
Publicado: (2018)

CD44 Expression Predicts Prognosis of Ovarian Cancer Patients Through Promoting Epithelial-Mesenchymal Transition (EMT) by Regulating Snail, ZEB1, and Caveolin-1
por: Zhou, Jiayi, et al.
Publicado: (2019)

BRD7 suppresses tumor chemosensitivity to CHK1 inhibitors by inhibiting USP1-mediated deubiquitination of CHK1
por: Li, Lemin, et al.
Publicado: (2023)

Regulation of Chk1
por: Tapia-Alveal, Claudia, et al.
Publicado: (2009)

Gastrulation EMT Is Independent of P-Cadherin Downregulation
por: Moly, Pricila K., et al.
Publicado: (2016)

Cadherin Expression and EMT: A Focus on Gliomas
por: Noronha, Carolina, et al.
Publicado: (2021)

Induction of epithelial-mesenchymal transition (EMT) by Beclin 1 knockdown via posttranscriptional upregulation of ZEB1 in thyroid cancer cells
por: Li, Si, et al.
Publicado: (2016)

GRHL2 Acts as an Anti-Oncogene in Bladder Cancer by Regulating ZEB1 in Epithelial-Mesenchymal Transition (EMT) Process
por: Shen, Jingang, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_2o0vj2qncknqj7o31bfpmusv07