Cargando…

TELO2 induced progression of colorectal cancer by binding with RICTOR through mTORC2

Colorectal cancer (CRC) is a common cancer worldwide, and its treatment strategies are limited. The underlying mechanism of CRC progression remains to be determined. Telomere maintenance 2 (TELO2) is a mTOR-interacting protein. Both the role and molecular mechanism of TELO2 in cancer progression rem...

Descripción completa

Detalles Bibliográficos
Autores principales:	Guo, Zheng, Zhang, Xiufang, Zhu, Huabin, Zhong, Nanying, Luo, Xiaoning, Zhang, Yu, Tu, Fuping, Zhong, Jinghua, Wang, Xiangcai, He, Jue, Huang, Li
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2021
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7757093/ https://www.ncbi.nlm.nih.gov/pubmed/33416177 http://dx.doi.org/10.3892/or.2020.7890

Ejemplares similares

Transmembrane Inhibitor of RICTOR/mTORC2 in Hematopoietic Progenitors
por: Lee, Dongjun, et al.
Publicado: (2014)

Inhibition of mTORC2/RICTOR Impairs Melanoma Hepatic Metastasis()()
por: Schmidt, Katharina M., et al.
Publicado: (2018)

Rictor/mTORC2 facilitates central regulation of energy and glucose homeostasis
por: Kocalis, Heidi E., et al.
Publicado: (2014)

PTH(1-34) activates the migration and adhesion of BMSCs through the rictor/mTORC2 pathway
por: Lv, Zhong, et al.
Publicado: (2020)

Depletion of Rictor, an essential protein component of mTORC2, decreases male lifespan
por: Lamming, Dudley W, et al.
Publicado: (2014)

The mTORC2 Component Rictor Contributes to Cisplatin Resistance in Human Ovarian Cancer Cells
por: Im-aram, Akechai, et al.
Publicado: (2013)

Involvement of Rictor/mTORC2 in cardiomyocyte differentiation of mouse embryonic stem cells in vitro
por: Zheng, Bei, et al.
Publicado: (2017)

Inhibition of mTORC2 component RICTOR impairs tumor growth in pancreatic cancer models
por: Schmidt, Katharina M., et al.
Publicado: (2017)

microRNA-153 Targets mTORC2 Component Rictor to Inhibit Glioma Cells
por: Cui, Yan, et al.
Publicado: (2016)

Ablation of the mTORC2 component rictor in brain or Purkinje cells affects size and neuron morphology
por: Thomanetz, Venus, et al.
Publicado: (2013)

Specific blockade of Rictor-mTOR association inhibits mTORC2 activity and is cytotoxic in glioblastoma
por: Benavides-Serrato, Angelica, et al.
Publicado: (2017)

Activation of Rictor/mTORC2 signaling acts as a pivotal strategy to protect against sensorineural hearing loss
por: Fu, Xiaolong, et al.
Publicado: (2022)

RICTOR/mTORC2 affects tumorigenesis and therapeutic efficacy of mTOR inhibitors in esophageal squamous cell carcinoma
por: Lu, Zhaoming, et al.
Publicado: (2020)

mTORC2/RICTOR exerts differential levels of metabolic control in human embryonic, mesenchymal and neural stem cells
por: Chu, Qun, et al.
Publicado: (2022)

Rictor/mTORC2 Is Essential for Maintaining a Balance Between β-Cell Proliferation and Cell Size
por: Gu, Yanyun, et al.
Publicado: (2011)

Rictor/mTORC2 signaling mediates TGFβ1-induced fibroblast activation and kidney fibrosis
por: Li, Jianzhong, et al.
Publicado: (2015)

Correction: Specific blockade of Rictor-mTOR association inhibits mTORC2 activity and is cytotoxic in glioblastoma
por: Benavides-Serrato, Angelica, et al.
Publicado: (2019)

The mTORC2 Component Rictor Is Required for Load‐Induced Bone Formation in Late‐Stage Skeletal Cells
por: Lewis, Karl J, et al.
Publicado: (2020)

Retraction: Specific blockade of Rictor-mTOR association inhibits mTORC2 activity and is cytotoxic in glioblastoma
Publicado: (2023)

PTEN negatively regulates mTORC2 formation and signaling in grade IV glioma via Rictor hyperphosphorylation at Thr1135 and direct the mode of action of an mTORC1/2 inhibitor
por: Bhattacharya, K, et al.
Publicado: (2016)

Correction to: mTORC2/RICTOR exerts differential levels of metabolic control in human embryonic, mesenchymal and neural stem cells
por: Chu, Qun, et al.
Publicado: (2022)

Mdm20 Modulates Actin Remodeling through the mTORC2 Pathway via Its Effect on Rictor Expression
por: Yasuda, Kunihiko, et al.
Publicado: (2015)

Opposing Tumor-Promoting and -Suppressive Functions of Rictor/mTORC2 Signaling in Adult Glioma and Pediatric SHH Medulloblastoma
por: Akgül, Seçkin, et al.
Publicado: (2018)

Rictor/mTORC2 involves mitochondrial function in ES cells derived cardiomyocytes via mitochondrial Connexin 43
por: Wang, Jia-dan, et al.
Publicado: (2021)

The Deubiquitinase USP39 Promotes ESCC Tumorigenesis Through Pre-mRNA Splicing of the mTORC2 Component Rictor
por: Zhao, Yuan, et al.
Publicado: (2021)

Telos.
Publicado: (1985)

Prediction of Hepatocellular Carcinoma Response to Transcatheter Arterial Chemoembolization: A Real-World Study Based on Non-Contrast Computed Tomography Radiomics and General Image Features
por: Guo, Zheng, et al.
Publicado: (2021)

Disruption of the RICTOR/mTORC2 complex enhances the response of head and neck squamous cell carcinoma cells to PI3K inhibition
por: Ruicci, Kara M., et al.
Publicado: (2019)

mTORC1 and mTORC2 in cancer and the tumor microenvironment
por: Kim, Laura C., et al.
Publicado: (2016)

Pathogenic Role of mTORC1 and mTORC2 in Pulmonary Hypertension
por: Tang, Haiyang, et al.
Publicado: (2018)

Telos : revelaciones de la Nueva Lemuria
por: Jones, Aurelia Louise
Publicado: (2004)

mTORC2/AKT/HSF1/HuR constitute a feed-forward loop regulating Rictor expression and tumor growth in glioblastoma
por: Holmes, Brent, et al.
Publicado: (2017)

Erratum to: Disruption of the RICTOR/mTORC2 complex enhances the response of head and neck squamous cell carcinoma cells to PI3K inhibition
por: Ruicci, Kara M., et al.
Publicado: (2019)

Fibroblast growth factor 1 ameliorates adipose tissue inflammation and systemic insulin resistance via enhancing adipocyte mTORC2/Rictor signal
por: Zhao, Longwei, et al.
Publicado: (2020)

Correction for Fu et al., Activation of Rictor/mTORC2 signaling acts as a pivotal strategy to protect against sensorineural hearing loss
Publicado: (2022)

Both mTORC1 and mTORC2 are involved in the regulation of cell adhesion
por: Chen, Long, et al.
Publicado: (2015)

The metabolic waste ammonium regulates mTORC2 and mTORC1 signaling
por: Merhi, Ahmad, et al.
Publicado: (2017)

Differential controls of MAIT cell effector polarization by mTORC1/mTORC2 via integrating cytokine and costimulatory signals
por: Tao, Huishan, et al.
Publicado: (2021)

Rapamycin inhibits mSin1 phosphorylation independently of mTORC1 and mTORC2
por: Luo, Yan, et al.
Publicado: (2015)

mTORC1 and mTORC2 regulate skin morphogenesis and epidermal barrier formation
por: Ding, Xiaolei, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_cebmhjb3ctvprdh113365jcpjd