Cargando…

Genetically Engineered Mouse Model of Brainstem High-Grade Glioma

Brainstem gliomas are aggressive tumors that are more prevalent in pediatric patients. The location of these tumors makes them inoperable, and currently there is no effective treatment. Recent genomic data revealed the unique biology of these tumors. The following protocol provides a method to incor...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nunez, Fernando M., Gauss, Jessica C., Mendez, Flor M., Haase, Santiago, Lowenstein, Pedro R., Castro, Maria G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2020
Materias:	Protocol
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7757359/ https://www.ncbi.nlm.nih.gov/pubmed/33377059 http://dx.doi.org/10.1016/j.xpro.2020.100165

Ejemplares similares

Hemispherical Pediatric High-Grade Glioma: Molecular Basis and Therapeutic Opportunities
por: Haase, Santiago, et al.
Publicado: (2020)

Immune-stimulatory (TK/Flt3L) gene therapy opens the door to a promising new treatment strategy against brainstem gliomas
por: Faisal, Syed M., et al.
Publicado: (2020)

Inducing primary brainstem gliomas in genetically engineered mice using RCAS/TVA retroviruses and Cre/loxP recombination
por: Weidenhammer, Loren B., et al.
Publicado: (2023)

An Optimized Protocol for In Vivo Analysis of Tumor Cell Division in a Sleeping Beauty-Mediated Mouse Glioma Model
por: Garcia-Fabiani, Maria B., et al.
Publicado: (2020)

An affinity for brainstem microglia in pediatric high-grade gliomas of brainstem origin
por: Zats, Liat Peretz, et al.
Publicado: (2022)

Impact of epigenetic reprogramming on antitumor immune responses in glioma
por: McClellan, Brandon L., et al.
Publicado: (2023)

H3.3-G34R Mutation-Mediated Epigenetic Reprogramming Leads to Enhanced Efficacy of Immune Stimulatory Gene Therapy in Pediatric High-Grade Gliomas
por: Garcia-Fabiani, Maria B., et al.
Publicado: (2023)

Generation of 3D ex vivo mouse- and patient-derived glioma explant slice model for integration of confocal time-lapse imaging and spatial analysis
por: Comba, Andrea, et al.
Publicado: (2023)

The genomic landscape of diffuse intrinsic pontine glioma and pediatric non-brainstem high-grade glioma
por: Wu, Gang, et al.
Publicado: (2014)

PD-0332991, a CDK4/6 Inhibitor, Significantly Prolongs Survival in a Genetically Engineered Mouse Model of Brainstem Glioma
por: Barton, Kelly L., et al.
Publicado: (2013)

Uncovering Spatiotemporal Heterogeneity of High-Grade Gliomas: From Disease Biology to Therapeutic Implications
por: Comba, Andrea, et al.
Publicado: (2021)

Brainstem Glioma in Adults
por: Hu, Jethro, et al.
Publicado: (2016)

Angiocentric glioma of brainstem
por: Almubarak, Abdulaziz O., et al.
Publicado: (2020)

Genetic and immune features of resectable malignant brainstem gliomas
por: Zhang, Yang, et al.
Publicado: (2017)

Leptomeningeal Dissemination of a Low-Grade Brainstem Glioma without Local Recurrence
por: Moon, Jung-Ho, et al.
Publicado: (2012)

Identification of Grade-associated MicroRNAs in Brainstem Gliomas Based on Microarray Data
por: Chen, Xin, et al.
Publicado: (2018)

HGG-17. Novel Fusion in Congenital Brainstem Diffuse High-Grade Glioma
por: Norris, Gregory, et al.
Publicado: (2022)

Analysis of survival in pediatric high-grade brainstem gliomas: A population-based study
por: Lam, Sandi, et al.
Publicado: (2015)

PATH-10. PROGNOSTIC RELEVANT IMMUNOPHENOTYPES OF PEDIATRIC HIGH-GRADE NON-BRAINSTEM GLIOMAS
por: Mikhaleuskaya, Taisiya, et al.
Publicado: (2020)

Protocol for integrative subtyping of lower-grade gliomas using the SUMO pipeline
por: Sienkiewicz, Karolina, et al.
Publicado: (2022)

Genetic Alterations in Gliomas Remodel the Tumor Immune Microenvironment and Impact Immune-Mediated Therapies
por: Garcia-Fabiani, Maria B., et al.
Publicado: (2021)

Management and Outcomes of Low-Grade Gliomas in Africa: A Scoping Review Protocol
por: Ooi, Setthasorn Zhi Yang, et al.
Publicado: (2022)

Current Approaches for Glioma Gene Therapy and Virotherapy
por: Banerjee, Kaushik, et al.
Publicado: (2021)

Protocol to establish a genetically engineered mouse model of IDH1-mutant astrocytoma
por: Shi, Diana D., et al.
Publicado: (2023)

H3.3-G34 mutations impair DNA repair and promote cGAS/STING-mediated immune responses in pediatric high-grade glioma models
por: Haase, Santiago, et al.
Publicado: (2022)

Development of immunotherapy for high-grade gliomas: Overcoming the immunosuppressive tumor microenvironment
por: Franson, Andrea, et al.
Publicado: (2022)

Pediatric Brainstem Gliomas: An Institutional Experience
por: Laghari, Altaf Ali, et al.
Publicado: (2019)

A treatment planning comparison of highly conformal radiation therapy for pediatric low-grade brainstem gliomas
por: Brower, Jeffrey V., et al.
Publicado: (2013)

The integrated genomic and epigenomic landscape of brainstem glioma
por: Chen, Lee H., et al.
Publicado: (2020)

Murine brain tumor microenvironment immunophenotyping using mass cytometry
por: McClellan, Brandon L., et al.
Publicado: (2022)

Tumor mutational burden predicts survival in patients with low-grade gliomas expressing mutated IDH1
por: Alghamri, Mahmoud S, et al.
Publicado: (2020)

Focal brainstem gliomas: Advances in intra-operative management
por: Sabbagh, Abdulrahman J., et al.
Publicado: (2015)

Role of neuronavigation in the surgical management of brainstem gliomas
por: Zhang, Mingxin, et al.
Publicado: (2023)

EPID-01. Differences in first-line treatment but comparable survival outcomes for pediatric brainstem and non-brainstem high-grade gliomas in the Netherlands – a population-based study
por: Hoogendijk, Raoull, et al.
Publicado: (2022)

Assembly of the Auditory Circuitry by a Hox Genetic Network in the Mouse Brainstem
por: Di Bonito, Maria, et al.
Publicado: (2013)

The Effect of Atm Loss on Radiosensitivity of a Primary Mouse Model of Pten-Deleted Brainstem Glioma
por: Stewart, Connor E., et al.
Publicado: (2022)

Genetically Engineered Mouse Models of Gliomas: Technological Developments for Translational Discoveries
por: Noorani, Imran
Publicado: (2019)

Characterizing and targeting PDGFRA alterations in pediatric high-grade glioma
por: Koschmann, Carl, et al.
Publicado: (2016)

Genetic engineering of human and mouse CD4(+) and CD8(+) Tregs using lentiviral vectors encoding chimeric antigen receptors
por: Vimond, Nadège, et al.
Publicado: (2020)

Protocol to assess the antitumor efficacy of an immunotherapeutic peptide in syngeneic orthotopic glioma mouse models
por: Chen, Apeng, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_or3e9n1ff2rg8nuef7cr9hkpj1