Cargando…

Preclinical Testing of CAR T Cells in a Patient-Derived Xenograft Model of Glioblastoma

Glioblastoma (GBM) is the most common malignant adult brain tumor that is resistant to the standard care therapy. Advances in chimeric antigen receptor (CAR) T cell therapies have spurred renewed interest in developing CAR T cell therapies to target chemoradiotherapy-resistant brain tumor-initiating...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tatari, Nazanin, Maich, William T., Salim, Sabra K., Mckenna, Dillon, Venugopal, Chitra, Singh, Sheila
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2020
Materias:	Protocol
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7757398/ https://www.ncbi.nlm.nih.gov/pubmed/33377068 http://dx.doi.org/10.1016/j.xpro.2020.100174

Ejemplares similares

In vitro evaluation of CAR-T cells in patient-derived glioblastoma models
por: Brakel, Benjamin A., et al.
Publicado: (2021)

A Patient-Derived Xenograft Model of Glioblastoma
por: Chokshi, Chirayu R., et al.
Publicado: (2020)

SYST-33 GENERATION OF ALLOGENEIC CAR-T CIRCUMVENTS FUNCTIONAL DEFICITS IN PATIENT-DERIVED AUTOLOGOUS PRODUCT FOR GLIOBLASTOMA
por: Shaikh, Muhammad Vaseem, et al.
Publicado: (2023)

Advances in Immunotherapy for Adult Glioblastoma
por: Chokshi, Chirayu R., et al.
Publicado: (2021)

AUTOLOGOUS PATIENT-DERIVED CAR-TS SHOW FUNCTIONAL DEFICITS AGAINST HUMAN GLIOBLASTOMA
por: Salim, Sabra K, et al.
Publicado: (2023)

CD70 as an actionable immunotherapeutic target in recurrent glioblastoma and its microenvironment
por: Seyfrid, Mathieu, et al.
Publicado: (2022)

SYST-26 INVESTIGATING THE FUNCTIONAL ROLE OF GPNMB IN GLIOBLASTOMA AND THE TUMOR IMMUNE MICROENVIRONMENT AND ITS TARGETED ELIMINATION USING CAR-T CELLS
por: Savage, Neil, et al.
Publicado: (2023)

Assessing the Safety of a Cell-Based Immunotherapy for Brain Cancers Using a Humanized Model of Hematopoiesis
por: Salim, Sabra K., et al.
Publicado: (2020)

GENETIC SCREENING REVEALS DEPENDENCY ON FEN1 TO RESIST TEMOZOLOMIDE IN TREATMENT-RESISTANT GLIOBLASTOMA STEM CELLS
por: Brakel, Benjamin, et al.
Publicado: (2023)

The Strange Case of Jekyll and Hyde: Parallels Between Neural Stem Cells and Glioblastoma-Initiating Cells
por: Bakhshinyan, David, et al.
Publicado: (2021)

Optimized creation of glioblastoma patient derived xenografts for use in preclinical studies
por: William, Doreen, et al.
Publicado: (2017)

Generation of Glioblastoma Patient-Derived Intracranial Xenografts for Preclinical Studies
por: Kerstetter-Fogle, Amber E., et al.
Publicado: (2020)

Derivation and culturing of neural stem cells from human embryonic brain tissue
por: Suk, Yujin, et al.
Publicado: (2022)

UPAR AS A NOVEL IMMUNOTHERAPEUTIC TARGET IN RECURRENT GLIOBLASTOMA
por: Maich, William, et al.
Publicado: (2023)

Generation of glioblastoma patient-derived organoids and mouse brain orthotopic xenografts for drug screening
por: Gamboa, Christian Moya, et al.
Publicado: (2021)

47. UNCOVERING A NOVEL ROLE FOR HLA-G IN BRAIN METASTASES
por: Bassey-Archibong, Blessing, et al.
Publicado: (2020)

Dual Antigen T Cell Engagers Targeting CA9 as an Effective Immunotherapeutic Modality for Targeting CA9 in Solid Tumors
por: Tatari, Nazanin, et al.
Publicado: (2022)

ROBO1 CAR-T CELL THERAPY FOR TREATMENT REFRACTORY BRAIN CANCER
por: Shaikh, Muhammad Vaseem, et al.
Publicado: (2023)

A Preclinical Embryonic Zebrafish Xenograft Model to Investigate CAR T Cells in Vivo
por: Pascoal, Susana, et al.
Publicado: (2020)

High-dimensional functional phenotyping of preclinical human CAR T cells using mass cytometry
por: Michelozzi, Ilaria M., et al.
Publicado: (2022)

Preclinical Modeling and Therapeutic Avenues for Cancer Metastasis to the Central Nervous System
por: Singh, Mohini, et al.
Publicado: (2017)

Preclinical testing of oncolytic adenovirus sensitivity in patient-derived tumor organoids
por: Pascual-Sabater, Silvia, et al.
Publicado: (2021)

Establishment and Use of Patient-Derived Xenograft Models for Drug Testing in Head and Neck Squamous Cell Carcinoma
por: Karamboulas, Christina, et al.
Publicado: (2020)

Patient-derived xenografts as preclinical neuroblastoma models
por: Braekeveldt, Noémie, et al.
Publicado: (2017)

The Road to CAR T-Cell Therapies for Pediatric CNS Tumors: Obstacles and New Avenues
por: Burns, Ian, et al.
Publicado: (2022)

An Improved Protocol for Establishment of AML Patient-Derived Xenograft Models
por: Hassan, Nunki, et al.
Publicado: (2020)

SYST-28 FUNCTIONAL MAPPING REVEALS WIDESPREAD REMODELLING AND A NOVEL TARGETABLE PTP4A2-ROBO1 SIGNALING AXIS AT GLIOBLASTOMA RECURRENCE
por: Chokshi, Chirayu, et al.
Publicado: (2023)

Protocol for derivation of organoids and patient-derived orthotopic xenografts from glioma patient tumors
por: Oudin, Anaïs, et al.
Publicado: (2021)

Patient-derived xenograft model for uterine leiomyoma by sub-renal capsule grafting
por: Serna, Vanida Ann, et al.
Publicado: (2018)

Generating patient-derived ascites-dependent xenograft mouse models of peritoneal carcinomatosis
por: Liu, Ying, et al.
Publicado: (2022)

PATIENT-DERIVED XENOGRAFTS AS A PRECLINICAL MODEL FOR BONE SARCOMAS
por: MEOHAS, WALTER, et al.
Publicado: (2018)

Patient-Derived Xenograft Models of Epithelial Ovarian Cancer for Preclinical Studies
por: Heo, Eun Jin, et al.
Publicado: (2017)

Establishment and Characterisation of Heterotopic Patient-Derived Xenografts for Glioblastoma
por: Meneceur, Sarah, et al.
Publicado: (2020)

Generation of orthotopic patient-derived xenograft models for pancreatic cancer using tumor slices
por: Curiel-Garcia, Alvaro, et al.
Publicado: (2022)

Accelerating development of high-risk neuroblastoma patient-derived xenograft models for preclinical testing and personalised therapy
por: Kamili, Alvin, et al.
Publicado: (2020)

PCAT: an integrated portal for genomic and preclinical testing data of pediatric cancer patient-derived xenograft models
por: Yang, Juechen, et al.
Publicado: (2020)

Protocol to generate a patient derived xenograft model of acquired resistance to immunotherapy in humanized mice
por: Martínez-Sabadell, Alex, et al.
Publicado: (2022)

Preclinical testing of chimeric antigen receptor T cells in neuroblastoma mouse models
por: Li, Nan, et al.
Publicado: (2021)

Patient-derived xenografts: a relevant preclinical model for drug development
por: Pompili, Luca, et al.
Publicado: (2016)

Patient-derived xenografts: a promising resource for preclinical cancer research
por: Karamboulas, Christina, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_7nn6tclevrbq23pv3asnfnitql