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Protocol for Establishing Mouse Embryonic Stem Cells to Study Histone Inheritance Pattern at Single-Cell Resolution

Asymmetric histone inheritance can regulate cell-fate determination in Drosophila male germline stem cells. However, it remains elusive how this mechanism may be used in mammalian system. Recently, we show mouse embryonic stem cells (mESCs) with Wnt3a beads display non-overlapping H3/H4 patterns. He...

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Detalles Bibliográficos
Autores principales: Ma, Binbin, Trieu, Tung-Jui, Habib, Shukry J., Chen, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7757403/
https://www.ncbi.nlm.nih.gov/pubmed/33377072
http://dx.doi.org/10.1016/j.xpro.2020.100178