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Factors associated with optimal patient outcomes after operative repair of isolated hip fractures in the elderly

BACKGROUND: Increased time to operative intervention is associated with a greater risk of mortality and complications in adults with a hip fracture. This study sought to determine factors associated with timeliness of operation in elderly patients presenting with an isolated hip fracture and the inf...

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Autores principales: deMeireles, Alirio J, Gerhardinger, Laura, Oliphant, Bryant W, Jenkins, Peter C, Cain-Nielsen, Anne H, Scott, John W, Hemmila, Mark R, Sangji, Naveen F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7757513/
https://www.ncbi.nlm.nih.gov/pubmed/33376809
http://dx.doi.org/10.1136/tsaco-2020-000630
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author deMeireles, Alirio J
Gerhardinger, Laura
Oliphant, Bryant W
Jenkins, Peter C
Cain-Nielsen, Anne H
Scott, John W
Hemmila, Mark R
Sangji, Naveen F
author_facet deMeireles, Alirio J
Gerhardinger, Laura
Oliphant, Bryant W
Jenkins, Peter C
Cain-Nielsen, Anne H
Scott, John W
Hemmila, Mark R
Sangji, Naveen F
author_sort deMeireles, Alirio J
collection PubMed
description BACKGROUND: Increased time to operative intervention is associated with a greater risk of mortality and complications in adults with a hip fracture. This study sought to determine factors associated with timeliness of operation in elderly patients presenting with an isolated hip fracture and the influence of surgical delay on outcomes. METHODS: Trauma quality collaborative data (July 2016 to June 2019) were analyzed. Inclusion criteria were patients ≥65 years with an injury mechanism of fall, Abbreviated Injury Scale (AIS) 2005 diagnosis of hip fracture, and AIS extremity ≤3. Exclusion criteria included AIS in other body regions >1 and non-operative management. We examined the association of demographic, hospital, injury presentation, and comorbidity factors on a surgical delay >48 hours and patient outcomes using multivariable regression analysis. RESULTS: 10 182 patients fit our study criteria out of 212 620 patients. Mean age was 82.7±8.6 years and 68.7% were female. Delay in operation >48 hours occurred in 965 (9.5%) of patients. Factors that significantly increased mortality or discharge to hospice were increased age, male gender, emergency department hypotension, functionally dependent health status (FDHS), advanced directive, liver disease, angina, and congestive heart failure (CHF). Delay >48 hours was associated with increased mortality or discharge to hospice (OR 1.52; 95% CI 1.13 to 2.06; p<0.01). Trauma center verification level, admission service, and hip fracture volume were not associated with mortality or discharge to hospice. Factors associated with operative delay >48 hours were male gender, FDHS, CHF, chronic renal failure, and advanced directive. Admission to the orthopedic surgery service was associated with less incidence of delay >48 hours (OR 0.43; 95% CI 0.29 to 0.64; p<0.001). DISCUSSION: Hospital verification level, admission service, and patient volume did not impact the outcome of mortality/discharge to hospice. Delay to operation >48 hours was associated with increased mortality. The only measured modifiable characteristic that reduced delay to operative intervention was admission to the orthopedic surgery service. LEVEL OF EVIDENCE: III.
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spelling pubmed-77575132020-12-28 Factors associated with optimal patient outcomes after operative repair of isolated hip fractures in the elderly deMeireles, Alirio J Gerhardinger, Laura Oliphant, Bryant W Jenkins, Peter C Cain-Nielsen, Anne H Scott, John W Hemmila, Mark R Sangji, Naveen F Trauma Surg Acute Care Open Original Research BACKGROUND: Increased time to operative intervention is associated with a greater risk of mortality and complications in adults with a hip fracture. This study sought to determine factors associated with timeliness of operation in elderly patients presenting with an isolated hip fracture and the influence of surgical delay on outcomes. METHODS: Trauma quality collaborative data (July 2016 to June 2019) were analyzed. Inclusion criteria were patients ≥65 years with an injury mechanism of fall, Abbreviated Injury Scale (AIS) 2005 diagnosis of hip fracture, and AIS extremity ≤3. Exclusion criteria included AIS in other body regions >1 and non-operative management. We examined the association of demographic, hospital, injury presentation, and comorbidity factors on a surgical delay >48 hours and patient outcomes using multivariable regression analysis. RESULTS: 10 182 patients fit our study criteria out of 212 620 patients. Mean age was 82.7±8.6 years and 68.7% were female. Delay in operation >48 hours occurred in 965 (9.5%) of patients. Factors that significantly increased mortality or discharge to hospice were increased age, male gender, emergency department hypotension, functionally dependent health status (FDHS), advanced directive, liver disease, angina, and congestive heart failure (CHF). Delay >48 hours was associated with increased mortality or discharge to hospice (OR 1.52; 95% CI 1.13 to 2.06; p<0.01). Trauma center verification level, admission service, and hip fracture volume were not associated with mortality or discharge to hospice. Factors associated with operative delay >48 hours were male gender, FDHS, CHF, chronic renal failure, and advanced directive. Admission to the orthopedic surgery service was associated with less incidence of delay >48 hours (OR 0.43; 95% CI 0.29 to 0.64; p<0.001). DISCUSSION: Hospital verification level, admission service, and patient volume did not impact the outcome of mortality/discharge to hospice. Delay to operation >48 hours was associated with increased mortality. The only measured modifiable characteristic that reduced delay to operative intervention was admission to the orthopedic surgery service. LEVEL OF EVIDENCE: III. BMJ Publishing Group 2020-12-22 /pmc/articles/PMC7757513/ /pubmed/33376809 http://dx.doi.org/10.1136/tsaco-2020-000630 Text en © Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. http://creativecommons.org/licenses/by-nc/4.0/ http://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.
spellingShingle Original Research
deMeireles, Alirio J
Gerhardinger, Laura
Oliphant, Bryant W
Jenkins, Peter C
Cain-Nielsen, Anne H
Scott, John W
Hemmila, Mark R
Sangji, Naveen F
Factors associated with optimal patient outcomes after operative repair of isolated hip fractures in the elderly
title Factors associated with optimal patient outcomes after operative repair of isolated hip fractures in the elderly
title_full Factors associated with optimal patient outcomes after operative repair of isolated hip fractures in the elderly
title_fullStr Factors associated with optimal patient outcomes after operative repair of isolated hip fractures in the elderly
title_full_unstemmed Factors associated with optimal patient outcomes after operative repair of isolated hip fractures in the elderly
title_short Factors associated with optimal patient outcomes after operative repair of isolated hip fractures in the elderly
title_sort factors associated with optimal patient outcomes after operative repair of isolated hip fractures in the elderly
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7757513/
https://www.ncbi.nlm.nih.gov/pubmed/33376809
http://dx.doi.org/10.1136/tsaco-2020-000630
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