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Spaeth/Richman Contrast Sensitivity in Staging Glaucoma
PURPOSE: To investigate contrast sensitivity measures in glaucoma eyes with moderate to severe glaucoma. METHODS: The study included 50 eyes of 47 pseudophakic patients with moderate or severe glaucoma who were seen at a tertiary center from 2017 to 2020. Assessment of contrast sensitivity using the...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Association for Research in Vision and Ophthalmology
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7757629/ https://www.ncbi.nlm.nih.gov/pubmed/33384893 http://dx.doi.org/10.1167/tvst.9.13.39 |
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author | Rao, Aparna Pal, Anindita Mohapatra, Shreya |
author_facet | Rao, Aparna Pal, Anindita Mohapatra, Shreya |
author_sort | Rao, Aparna |
collection | PubMed |
description | PURPOSE: To investigate contrast sensitivity measures in glaucoma eyes with moderate to severe glaucoma. METHODS: The study included 50 eyes of 47 pseudophakic patients with moderate or severe glaucoma who were seen at a tertiary center from 2017 to 2020. Assessment of contrast sensitivity using the Spaeth/Richman contrast sensitivity (SPARCS) test and the Pelli–Robson (PR) chart was compared in eyes with mean deviation (MD) < –12 decibels (dB) and > –20 dB (group 1), MD < –20 dB and > –30 dB (group 2), or MD < –30 dB (group 3). Multivariate regression analysis was used to analyze the association of visual field MD with SPARCS/PR scores and various clinical variables, including age, diagnosis, and logMar visual acuity. RESULTS: SPARCS total scores and quadrant-wise scores were significantly different in all of the quadrants, whereas central scores and PR contrast sensitivity were similar across groups. The total SPARCS scores predicted the change in MD (β = 0.5, P < 0.001, R(2) = 61.8%) with minimal association of other quadrantic or PR scores. Total SPARCS scores of <45 and <38 predicted severe glaucoma with MD crossing –20 dB (sensitivity, 70.5%; specificity, 80.9%) and –30 dB (sensitivity, 79.3%; specificity, 77.7%), respectively. The logMar visual acuity did not correlate with any contrast sensitivity measure or clinical variables in this study. CONCLUSIONS: The total SPARCS score may be used in staging glaucoma severity and to assess visual function in eyes with severe glaucoma. TRANSLATIONAL RELEVANCE: The SPARCS test is a useful tool for assessing visual function in advanced glaucoma beyond MD worse than –20 dB or –30 dB. |
format | Online Article Text |
id | pubmed-7757629 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | The Association for Research in Vision and Ophthalmology |
record_format | MEDLINE/PubMed |
spelling | pubmed-77576292020-12-30 Spaeth/Richman Contrast Sensitivity in Staging Glaucoma Rao, Aparna Pal, Anindita Mohapatra, Shreya Transl Vis Sci Technol Article PURPOSE: To investigate contrast sensitivity measures in glaucoma eyes with moderate to severe glaucoma. METHODS: The study included 50 eyes of 47 pseudophakic patients with moderate or severe glaucoma who were seen at a tertiary center from 2017 to 2020. Assessment of contrast sensitivity using the Spaeth/Richman contrast sensitivity (SPARCS) test and the Pelli–Robson (PR) chart was compared in eyes with mean deviation (MD) < –12 decibels (dB) and > –20 dB (group 1), MD < –20 dB and > –30 dB (group 2), or MD < –30 dB (group 3). Multivariate regression analysis was used to analyze the association of visual field MD with SPARCS/PR scores and various clinical variables, including age, diagnosis, and logMar visual acuity. RESULTS: SPARCS total scores and quadrant-wise scores were significantly different in all of the quadrants, whereas central scores and PR contrast sensitivity were similar across groups. The total SPARCS scores predicted the change in MD (β = 0.5, P < 0.001, R(2) = 61.8%) with minimal association of other quadrantic or PR scores. Total SPARCS scores of <45 and <38 predicted severe glaucoma with MD crossing –20 dB (sensitivity, 70.5%; specificity, 80.9%) and –30 dB (sensitivity, 79.3%; specificity, 77.7%), respectively. The logMar visual acuity did not correlate with any contrast sensitivity measure or clinical variables in this study. CONCLUSIONS: The total SPARCS score may be used in staging glaucoma severity and to assess visual function in eyes with severe glaucoma. TRANSLATIONAL RELEVANCE: The SPARCS test is a useful tool for assessing visual function in advanced glaucoma beyond MD worse than –20 dB or –30 dB. The Association for Research in Vision and Ophthalmology 2020-12-22 /pmc/articles/PMC7757629/ /pubmed/33384893 http://dx.doi.org/10.1167/tvst.9.13.39 Text en Copyright 2020 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. |
spellingShingle | Article Rao, Aparna Pal, Anindita Mohapatra, Shreya Spaeth/Richman Contrast Sensitivity in Staging Glaucoma |
title | Spaeth/Richman Contrast Sensitivity in Staging Glaucoma |
title_full | Spaeth/Richman Contrast Sensitivity in Staging Glaucoma |
title_fullStr | Spaeth/Richman Contrast Sensitivity in Staging Glaucoma |
title_full_unstemmed | Spaeth/Richman Contrast Sensitivity in Staging Glaucoma |
title_short | Spaeth/Richman Contrast Sensitivity in Staging Glaucoma |
title_sort | spaeth/richman contrast sensitivity in staging glaucoma |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7757629/ https://www.ncbi.nlm.nih.gov/pubmed/33384893 http://dx.doi.org/10.1167/tvst.9.13.39 |
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