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Immunotherapy for Infarcts: In Vivo Postinfarction Macrophage Modulation Using Intramyocardial Microparticle Delivery of Map4k4 Small Interfering RNA

The myeloid cells infiltrating the heart early after acute myocardial infarction elaborate a secretome that largely orchestrates subsequent ventricular wall repair. Regulating this innate immune response could be a means to improve infarct healing. To pilot this concept, we utilized (β1,3-d-) glucan...

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Detalles Bibliográficos
Autores principales: Luo, Jun, Weaver, Matthew S., Fitzgibbons, Timothy P., Aouadi, Myriam, Czech, Michael P., Allen, Margaret D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7757732/
https://www.ncbi.nlm.nih.gov/pubmed/33376632
http://dx.doi.org/10.1089/biores.2020.0037