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Fluorescent indolizine derivative YI-13 detects amyloid-β monomers, dimers, and plaques in the brain of 5XFAD Alzheimer transgenic mouse model

Alzheimer disease (AD) is a neurodegenerative disorder characterized by the aberrant production and accumulation of amyloid-β (Aβ) peptides in the brain. Accumulated Aβ in soluble oligomer and insoluble plaque forms are considered to be a pathological culprit and biomarker of the disorder. Here, we...

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Detalles Bibliográficos
Autores principales:	Kim, DaWon, Lee, Jeong Hwa, Kim, Hye Yun, Shin, Jisu, Kim, Kyeonghwan, Lee, Sejin, Park, Jinwoo, Kim, JinIkyon, Kim, YoungSoo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7757811/ https://www.ncbi.nlm.nih.gov/pubmed/33362250 http://dx.doi.org/10.1371/journal.pone.0243041

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