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Fluorescent indolizine derivative YI-13 detects amyloid-β monomers, dimers, and plaques in the brain of 5XFAD Alzheimer transgenic mouse model
Alzheimer disease (AD) is a neurodegenerative disorder characterized by the aberrant production and accumulation of amyloid-β (Aβ) peptides in the brain. Accumulated Aβ in soluble oligomer and insoluble plaque forms are considered to be a pathological culprit and biomarker of the disorder. Here, we...
Autores principales: | Kim, DaWon, Lee, Jeong Hwa, Kim, Hye Yun, Shin, Jisu, Kim, Kyeonghwan, Lee, Sejin, Park, Jinwoo, Kim, JinIkyon, Kim, YoungSoo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7757811/ https://www.ncbi.nlm.nih.gov/pubmed/33362250 http://dx.doi.org/10.1371/journal.pone.0243041 |
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