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Acadesine suppresses TNF-α induced complement component 3 (C3), in retinal pigment epithelial (RPE) cells

RATIONALE: Age-related macular degeneration (AMD) is the most prevalent form of irreversible blindness in the developed world. Aging, inflammation and complement dysregulation affecting the retinal pigment epithelium (RPE), are considered significant contributors in its pathogenesis and several evid...

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Detalles Bibliográficos
Autores principales:	Efstathiou, Nikolaos E., Moustafa, Giannis A., Maidana, Daniel E., Konstantinou, Eleni K., Notomi, Shoji, Barbisan, Paulo R. T., Georgakopoulos, Constantine D., Miller, Joan W., Vavvas, Demetrios G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7757886/ https://www.ncbi.nlm.nih.gov/pubmed/33362238 http://dx.doi.org/10.1371/journal.pone.0244307

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