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The Contribution of VKORC1 and CYP2C9 Genetic Polymorphisms and Patients’ Demographic Characteristics with Warfarin Maintenance Doses: A Suggested Warfarin Dosing Algorithm

The requirement of varying doses of warfarin for different individuals can be explained by environmental and genetic factors. We evaluated the frequency of vitamin K epoxide reductase complex subunit 1 (VKORC1) and cytochrome P450 2C9 (CYP2C9) variants together with patientdemographic characteristic...

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Detalles Bibliográficos
Autores principales: Khaleqsefat, Esmat, Khalaj-Kondori, Mohammad, Jabarpour Bonyadi, Mortaza, Soraya, Hamid, Askari, Behnam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shaheed Beheshti University of Medical Sciences 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7757989/
https://www.ncbi.nlm.nih.gov/pubmed/33680011
http://dx.doi.org/10.22037/ijpr.2020.1101116