Cargando…
Donepezil and Rivastigmine: Pharmacokinetic Profile and Brain-targeting After Intramuscular Administration in Rats
Current palliative pharmacotherapy of Alzheimer’s disease based on the cholinergic hypothesis led to the development of four cholinesterase inhibitors. These compounds can bring prolongation of the symptom-free period in some patients. This is the first report directly comparing donepezil and rivast...
Autores principales: | Karasova, Jana Zdarova, Hrabinova, Martina, Krejciova, Marketa, Jun, Daniel, Kuca, Kamil |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Shaheed Beheshti University of Medical Sciences
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7758017/ https://www.ncbi.nlm.nih.gov/pubmed/33680013 http://dx.doi.org/10.22037/ijpr.2019.1100723 |
Ejemplares similares
-
Evaluation of Cholinesterase Activities During in Vivo Intoxication Using an Electrochemical Sensor Strip – Correlation With Intoxication Symptoms
por: Pohanka, Miroslav, et al.
Publicado: (2009) -
Concentration of Donepezil in the Cerebrospinal Fluid of AD Patients: Evaluation of Dosage Sufficiency in Standard Treatment Strategy
por: Valis, Martin, et al.
Publicado: (2016) -
Novel Bisquaternary Oximes—Reactivation of Acetylcholinesterase and Butyrylcholinesterase Inhibited by Paraoxon
por: Kuca, Kamil, et al.
Publicado: (2009) -
A comparison of the neuroprotective efficacy of newly developed oximes (K117, K127) and currently available oxime (obidoxime) in tabun-poisoned rats
por: Kassa, Jiri, et al.
Publicado: (2009) -
Effect of Seven Newly Synthesized and Currently Available Oxime Cholinesterase Reactivators on Cyclosarin-Intoxicated Rats
por: Karasova, Jana Zdarova, et al.
Publicado: (2009)