Distinct polymorphisms in a single herpesvirus gene are capable of enhancing virulence and mediating vaccinal resistance

Modified-live herpesvirus vaccines are widely used in humans and animals, but field strains can emerge that have a higher virulence and break vaccinal protection. Since the introduction of the first vaccine in the 1970s, Marek’s disease virus overcame the vaccine barrier by the acquisition of numero...

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Detalles Bibliográficos
Autores principales: Conradie, Andelé M., Bertzbach, Luca D., Trimpert, Jakob, Patria, Joseph N., Murata, Shiro, Parcells, Mark S., Kaufer, Benedikt B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7758048/
https://www.ncbi.nlm.nih.gov/pubmed/33306739
http://dx.doi.org/10.1371/journal.ppat.1009104

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7758048/
https://www.ncbi.nlm.nih.gov/pubmed/33306739
http://dx.doi.org/10.1371/journal.ppat.1009104

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