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Distinct polymorphisms in a single herpesvirus gene are capable of enhancing virulence and mediating vaccinal resistance
Modified-live herpesvirus vaccines are widely used in humans and animals, but field strains can emerge that have a higher virulence and break vaccinal protection. Since the introduction of the first vaccine in the 1970s, Marek’s disease virus overcame the vaccine barrier by the acquisition of numero...
Autores principales: | Conradie, Andelé M., Bertzbach, Luca D., Trimpert, Jakob, Patria, Joseph N., Murata, Shiro, Parcells, Mark S., Kaufer, Benedikt B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7758048/ https://www.ncbi.nlm.nih.gov/pubmed/33306739 http://dx.doi.org/10.1371/journal.ppat.1009104 |
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