The Mechanism and Management of Adverse Cardiac Reactions Induced by Immune Checkpoint Inhibitors Therapy

Immune checkpoint inhibitors (ICIs) therapy has recently been introduced to all kinds of cancers. The adverse reactions associated with this therapy have attracted much attention. The heart-related adverse reactions are mainly the immune-related myocarditis and heart failure. Cases of adverse cardia...

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Detalles Bibliográficos
Autores principales: Rong, Fangning, Ji, Kangting, Weng, Yingpei, Peng, Yangpei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7758147/
https://www.ncbi.nlm.nih.gov/pubmed/33381310
http://dx.doi.org/10.1155/2020/8367651
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author Rong, Fangning
Ji, Kangting
Weng, Yingpei
Peng, Yangpei
author_facet Rong, Fangning
Ji, Kangting
Weng, Yingpei
Peng, Yangpei
author_sort Rong, Fangning
collection PubMed
description Immune checkpoint inhibitors (ICIs) therapy has recently been introduced to all kinds of cancers. The adverse reactions associated with this therapy have attracted much attention. The heart-related adverse reactions are mainly the immune-related myocarditis and heart failure. Cases of adverse cardiac reactions caused by ICIs therapy have been clearly reported. However, the pathogenesis of the adverse cardiac reactions remains unclear. Therefore, this article briefly reviews the mechanism and management of adverse cardiac reactions caused by ICIs therapy.
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spelling pubmed-77581472020-12-29 The Mechanism and Management of Adverse Cardiac Reactions Induced by Immune Checkpoint Inhibitors Therapy Rong, Fangning Ji, Kangting Weng, Yingpei Peng, Yangpei Cardiol Res Pract Research Article Immune checkpoint inhibitors (ICIs) therapy has recently been introduced to all kinds of cancers. The adverse reactions associated with this therapy have attracted much attention. The heart-related adverse reactions are mainly the immune-related myocarditis and heart failure. Cases of adverse cardiac reactions caused by ICIs therapy have been clearly reported. However, the pathogenesis of the adverse cardiac reactions remains unclear. Therefore, this article briefly reviews the mechanism and management of adverse cardiac reactions caused by ICIs therapy. Hindawi 2020-12-16 /pmc/articles/PMC7758147/ /pubmed/33381310 http://dx.doi.org/10.1155/2020/8367651 Text en Copyright © 2020 Fangning Rong et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Rong, Fangning
Ji, Kangting
Weng, Yingpei
Peng, Yangpei
The Mechanism and Management of Adverse Cardiac Reactions Induced by Immune Checkpoint Inhibitors Therapy
title The Mechanism and Management of Adverse Cardiac Reactions Induced by Immune Checkpoint Inhibitors Therapy
title_full The Mechanism and Management of Adverse Cardiac Reactions Induced by Immune Checkpoint Inhibitors Therapy
title_fullStr The Mechanism and Management of Adverse Cardiac Reactions Induced by Immune Checkpoint Inhibitors Therapy
title_full_unstemmed The Mechanism and Management of Adverse Cardiac Reactions Induced by Immune Checkpoint Inhibitors Therapy
title_short The Mechanism and Management of Adverse Cardiac Reactions Induced by Immune Checkpoint Inhibitors Therapy
title_sort mechanism and management of adverse cardiac reactions induced by immune checkpoint inhibitors therapy
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7758147/
https://www.ncbi.nlm.nih.gov/pubmed/33381310
http://dx.doi.org/10.1155/2020/8367651
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