Neuroprotective Effects of the Anti-cancer Drug Lapatinib Against Epileptic Seizures via Suppressing Glutathione Peroxidase 4-Dependent Ferroptosis

Epilepsy is a complex neurological disorder characterized by recurrent and unprovoked seizures. Neuronal death process is implicated in the development of repetitive epileptic seizures. Therefore, cell death can be harnessed for ceasing seizures and epileptogenesis. Oxidative stress is regarded as a...

Descripción completa

Detalles Bibliográficos
Autores principales: Jia, Ji-Ning, Yin, Xi-Xi, Li, Qin, Guan, Qi-Wen, Yang, Nan, Chen, Kang-Ni, Zhou, Hong-Hao, Mao, Xiao-Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7758233/
https://www.ncbi.nlm.nih.gov/pubmed/33362556
http://dx.doi.org/10.3389/fphar.2020.601572

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7758233/
https://www.ncbi.nlm.nih.gov/pubmed/33362556
http://dx.doi.org/10.3389/fphar.2020.601572

Ejemplares similares