Cargando…

Targeting IL-1β in the Treatment of Atherosclerosis

The role of inflammation in atherosclerosis has been recognized several decades ago and existing treatments provide benefits in part through non-specific anti-inflammatory actions. Compared with other cytokines, interleukin-1β (IL-1β) is associated with acute and chronic inflammation. Anti-inflammat...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mai, Wuqian, Liao, Yuhua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7758244/ https://www.ncbi.nlm.nih.gov/pubmed/33362770 http://dx.doi.org/10.3389/fimmu.2020.589654

Ejemplares similares

Succinate/IL-1β Signaling Axis Promotes the Inflammatory Progression of Endothelial and Exacerbates Atherosclerosis
por: Xu, Jingwen, et al.
Publicado: (2022)

Dendritic Cell IL-1α and IL-1β Are Polyubiquitinated and Degraded by the Proteasome
por: Ainscough, Joseph S., et al.
Publicado: (2014)

The three cytokines IL-1β, IL-18, and IL-1α share related but distinct secretory routes
por: Tapia, Victor S., et al.
Publicado: (2019)

Unique Versus Redundant Functions of IL-1α and IL-1β in the Tumor Microenvironment
por: Voronov, Elena, et al.
Publicado: (2013)

Distinct Roles of IL-1β and IL-18 in NLRC4-Induced Autoinflammation
por: Sasaki, Yuki, et al.
Publicado: (2020)

Analysis of Serum Interleukin (IL)-1β and IL-18 in Systemic Lupus Erythematosus
por: Mende, Rachel, et al.
Publicado: (2018)

Determining distinct roles of IL-1α through generation of an IL-1α knockout mouse with no defect in IL-1β expression
por: Malireddi, R.K. Subbarao, et al.
Publicado: (2022)

Inflammasome/IL-1β Responses to Streptococcal Pathogens
por: LaRock, Christopher N., et al.
Publicado: (2015)

Acid-dependent Interleukin-1 (IL-1) Cleavage Limits Available Pro-IL-1β for Caspase-1 Cleavage
por: Edye, Michelle E., et al.
Publicado: (2015)

Prognostic and Immunological Role of FUN14 Domain Containing 1 in Pan-Cancer: Friend or Foe?
por: Yuan, Qingchen, et al.
Publicado: (2020)

IL-1β and the Intestinal Epithelial Tight Junction Barrier
por: Kaminsky, Lauren W., et al.
Publicado: (2021)

Additive or Synergistic Interactions Between IL-17A or IL-17F and TNF or IL-1β Depend on the Cell Type
por: Noack, Mélissa, et al.
Publicado: (2019)

Mammalian Target of Rapamycin (mTOR) and the Proteasome Attenuates IL-1β Expression in Primary Mouse Cardiac Fibroblasts
por: Torp, May-Kristin, et al.
Publicado: (2019)

IL-1β promotes IL-9-producing Th cell differentiation in IL-2-limiting conditions through the inhibition of BCL6
por: Canaria, D. Alejandro, et al.
Publicado: (2022)

Macrophage Foam Cell-Targeting Immunization Attenuates Atherosclerosis
por: Wang, Fazhan, et al.
Publicado: (2019)

Macrophage Metabolism As Therapeutic Target for Cancer, Atherosclerosis, and Obesity
por: Geeraerts, Xenia, et al.
Publicado: (2017)

Antcin K Inhibits TNF-α, IL-1β and IL-8 Expression in Synovial Fibroblasts and Ameliorates Cartilage Degradation: Implications for the Treatment of Rheumatoid Arthritis
por: Achudhan, David, et al.
Publicado: (2021)

Secretion of IL-1β From Monocytes in Gout Is Redox Independent
por: Alberts, Ben M., et al.
Publicado: (2019)

IL-1β Promotes Staphylococcus aureus Biofilms on Implants in vivo
por: Gutierrez Jauregui, Rodrigo, et al.
Publicado: (2019)

Aspartate Metabolism Facilitates IL-1β Production in Inflammatory Macrophages
por: Wang, Hao, et al.
Publicado: (2021)

Uncoupled pyroptosis and IL-1β secretion downstream of inflammasome signaling
por: Li, Yang, et al.
Publicado: (2023)

Mercury increases IL-1β and IL-18 secretion and intensifies coronary arteritis in an animal model of Kawasaki disease
por: Alphonse, Martin P., et al.
Publicado: (2023)

Varicella-Zoster Virus Infection Triggers Formation of an Interleukin-1β (IL-1β)-processing Inflammasome Complex
por: Nour, Adel M., et al.
Publicado: (2011)

Vasa Vasorum Angiogenesis: Key Player in the Initiation and Progression of Atherosclerosis and Potential Target for the Treatment of Cardiovascular Disease
por: Sedding, Daniel G., et al.
Publicado: (2018)

Inhibition of Sphingosine-1-Phosphate Receptor 2 Prevents Thoracic Aortic Dissection and Rupture
por: Pan, Guangwei, et al.
Publicado: (2021)

CRISPR/Cas9 based blockade of IL-10 signaling impairs lipid and tissue homeostasis to accelerate atherosclerosis
por: Shi, Haozhe, et al.
Publicado: (2022)

The Role of NLRP3 and IL-1β in the Pathogenesis of Inflammatory Bowel Disease
por: Mao, Liming, et al.
Publicado: (2018)

Dysregulated IL-1β Secretion in Autoinflammatory Diseases: A Matter of Stress?
por: Carta, Sonia, et al.
Publicado: (2017)

IL-1β is not critical to chronic heart dysfunction in mice with Chagas disease
por: Sousa Oliveira, Camila Victória, et al.
Publicado: (2022)

Wnt signaling enhances macrophage responses to IL-4 and promotes resolution of atherosclerosis
por: Weinstock, Ada, et al.
Publicado: (2021)

IL-23/IL-17 Axis Activates IL-1β-Associated Inflammasome in Macrophages and Generates an Auto-Inflammatory Response in a Subgroup of Patients With Bullous Pemphigoid
por: Le Jan, Sébastien, et al.
Publicado: (2019)

β-Glucan Size Controls Dectin-1-Mediated Immune Responses in Human Dendritic Cells by Regulating IL-1β Production
por: Elder, Matthew J., et al.
Publicado: (2017)

Serine Supports IL-1β Production in Macrophages Through mTOR Signaling
por: Chen, Siyuan, et al.
Publicado: (2020)

ATP-Induced IL-1β Specific Secretion: True Under Stringent Conditions
por: Stoffels, Monique, et al.
Publicado: (2015)

The significance of Agaricus blazei as an immunomodulator of the level of IL-17 in Balb/C mice with atherosclerosis
por: TONTOWIPUTRO, DICKY KURNIAWAN, et al.
Publicado: (2020)

Targeting IL-34/MCSF-1R Axis in Colon Cancer
por: Monteleone, Giovanni, et al.
Publicado: (2022)

Structure–Activity Relationship of Plesiomonas shigelloides Lipid A to the Production of TNF-α, IL-1β, and IL-6 by Human and Murine Macrophages
por: Kaszowska, Marta, et al.
Publicado: (2017)

Tumor NLRP3-Derived IL-1β Drives the IL-6/STAT3 Axis Resulting in Sustained MDSC-Mediated Immunosuppression
por: Tengesdal, Isak W., et al.
Publicado: (2021)

Canonical NF-κB p65, but Not p105, Contributes to IL-1β-Induced IL-8 Expression in Cardiac Fibroblasts
por: Mizuno, Masashi, et al.
Publicado: (2022)

Human metapneumovirus driven IFN-β production antagonizes macrophage transcriptional induction of IL1-β in response to bacterial pathogens
por: Loevenich, Simon, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_08qulo30l6i5fgso0rn3ffd965