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Integrative Analysis of Transcriptome-Wide Association Study and mRNA Expression Profiles Identifies Candidate Genes Associated With Idiopathic Pulmonary Fibrosis

Idiopathic pulmonary fibrosis (IPF) is a type of scarring lung disease characterized by a chronic, progressive, and irreversible decline in lung function. The genetic basis of IPF remains elusive. A transcriptome-wide association study (TWAS) of IPF was performed by FUSION using gene expression weig...

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Detalles Bibliográficos
Autores principales: Gong, Weiming, Guo, Ping, Liu, Lu, Guan, Qingbo, Yuan, Zhongshang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7758323/
https://www.ncbi.nlm.nih.gov/pubmed/33362862
http://dx.doi.org/10.3389/fgene.2020.604324