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α-Actinin-4 Promotes the Progression of Prostate Cancer Through the Akt/GSK-3β/β-Catenin Signaling Pathway
The first-line treatment for prostate cancer (PCa) is androgen ablation therapy. However, prostate tumors generally recur and progress to androgen-independent PCa (AIPC) within 2–3 years. α-Actinin-4 (ACTN4) is an actin-binding protein that belongs to the spectrin gene superfamily and acts as an onc...
Autores principales: | Park, Sungyeon, Kang, Minsoo, Kim, Suhyun, An, Hyoung-Tae, Gettemans, Jan, Ko, Jesang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7758325/ https://www.ncbi.nlm.nih.gov/pubmed/33363146 http://dx.doi.org/10.3389/fcell.2020.588544 |
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