Profiling of H3K27Ac Reveals the Influence of Asthma on the Epigenome of the Airway Epithelium

BACKGROUND: Asthma is a chronic airway disease driven by complex genetic–environmental interactions. The role of epigenetic modifications in bronchial epithelial cells (BECs) in asthma is poorly understood. METHODS: We piloted genome-wide profiling of the enhancer-associated histone modification H3K...

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Detalles Bibliográficos
Autores principales: McErlean, Peter, Kelly, Audrey, Dhariwal, Jaideep, Kirtland, Max, Watson, Julie, Ranz, Ismael, Smith, Janet, Saxena, Alka, Cousins, David J., Van Oosterhout, Antoon, Solari, Roberto, Edwards, Michael R., Johnston, Sebastian L., Lavender, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7758344/
https://www.ncbi.nlm.nih.gov/pubmed/33362848
http://dx.doi.org/10.3389/fgene.2020.585746

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