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Is CFTR an exchanger?: Regulation of HCO(3)(−)Transport and extracellular pH by CFTR
The disease, cystic fibrosis, is caused by the malfunction of the cystic fibrosis transmembrane conductance regulator. Expression of functional CFTR may normally regulate extracellular pH via control of bicarbonate efflux. Reports also suggest that the CFTR may be a Cl-/HCO3- exchanger. If true, thi...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7758359/ https://www.ncbi.nlm.nih.gov/pubmed/33376814 http://dx.doi.org/10.1016/j.bbrep.2020.100863 |