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Is CFTR an exchanger?: Regulation of HCO(3)(−)Transport and extracellular pH by CFTR

The disease, cystic fibrosis, is caused by the malfunction of the cystic fibrosis transmembrane conductance regulator. Expression of functional CFTR may normally regulate extracellular pH via control of bicarbonate efflux. Reports also suggest that the CFTR may be a Cl-/HCO3- exchanger. If true, thi...

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Detalles Bibliográficos
Autores principales: Massey, Marija K., Reiterman, Michael J., Mourad, Jad, Luckie, Douglas B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7758359/
https://www.ncbi.nlm.nih.gov/pubmed/33376814
http://dx.doi.org/10.1016/j.bbrep.2020.100863