COVID-19 coagulopathy: is it disseminated intravascular coagulation?

One of the significant complications of severe COVID-19 infections is a coagulopathy that seems to be related to the occurrence of venous and arterial thromboembolic disease. The coagulation changes mimic but are not identical to disseminated intravascular coagulation (DIC). The vast majority of pat...

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Detalles Bibliográficos
Autores principales: Levi, Marcel, Iba, Toshiaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Im - Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7758412/
https://www.ncbi.nlm.nih.gov/pubmed/33368021
http://dx.doi.org/10.1007/s11739-020-02601-y
Descripción
Sumario:One of the significant complications of severe COVID-19 infections is a coagulopathy that seems to be related to the occurrence of venous and arterial thromboembolic disease. The coagulation changes mimic but are not identical to disseminated intravascular coagulation (DIC). The vast majority of patients with COVID-19 do not meet the criteria for usual forms of DIC. In addition, there seem to be features of a strong local pulmonary thrombotic microangiopathy and direct endothelial cell infection and injury by the virus that affect the coagulopathic response to severe COVID-19. It seems COVID-19 leads to a distinct intravascular coagulation syndrome that may need separate diagnostic criteria.

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