COVID-19 coagulopathy: is it disseminated intravascular coagulation?

One of the significant complications of severe COVID-19 infections is a coagulopathy that seems to be related to the occurrence of venous and arterial thromboembolic disease. The coagulation changes mimic but are not identical to disseminated intravascular coagulation (DIC). The vast majority of pat...

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Detalles Bibliográficos
Autores principales: Levi, Marcel, Iba, Toshiaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Im - Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7758412/
https://www.ncbi.nlm.nih.gov/pubmed/33368021
http://dx.doi.org/10.1007/s11739-020-02601-y
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author Levi, Marcel
Iba, Toshiaki
author_facet Levi, Marcel
Iba, Toshiaki
author_sort Levi, Marcel
collection PubMed
description One of the significant complications of severe COVID-19 infections is a coagulopathy that seems to be related to the occurrence of venous and arterial thromboembolic disease. The coagulation changes mimic but are not identical to disseminated intravascular coagulation (DIC). The vast majority of patients with COVID-19 do not meet the criteria for usual forms of DIC. In addition, there seem to be features of a strong local pulmonary thrombotic microangiopathy and direct endothelial cell infection and injury by the virus that affect the coagulopathic response to severe COVID-19. It seems COVID-19 leads to a distinct intravascular coagulation syndrome that may need separate diagnostic criteria.
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spelling pubmed-77584122020-12-28 COVID-19 coagulopathy: is it disseminated intravascular coagulation? Levi, Marcel Iba, Toshiaki Intern Emerg Med Im - Review One of the significant complications of severe COVID-19 infections is a coagulopathy that seems to be related to the occurrence of venous and arterial thromboembolic disease. The coagulation changes mimic but are not identical to disseminated intravascular coagulation (DIC). The vast majority of patients with COVID-19 do not meet the criteria for usual forms of DIC. In addition, there seem to be features of a strong local pulmonary thrombotic microangiopathy and direct endothelial cell infection and injury by the virus that affect the coagulopathic response to severe COVID-19. It seems COVID-19 leads to a distinct intravascular coagulation syndrome that may need separate diagnostic criteria. Springer International Publishing 2020-12-24 2021 /pmc/articles/PMC7758412/ /pubmed/33368021 http://dx.doi.org/10.1007/s11739-020-02601-y Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Im - Review
Levi, Marcel
Iba, Toshiaki
COVID-19 coagulopathy: is it disseminated intravascular coagulation?
title COVID-19 coagulopathy: is it disseminated intravascular coagulation?
title_full COVID-19 coagulopathy: is it disseminated intravascular coagulation?
title_fullStr COVID-19 coagulopathy: is it disseminated intravascular coagulation?
title_full_unstemmed COVID-19 coagulopathy: is it disseminated intravascular coagulation?
title_short COVID-19 coagulopathy: is it disseminated intravascular coagulation?
title_sort covid-19 coagulopathy: is it disseminated intravascular coagulation?
topic Im - Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7758412/
https://www.ncbi.nlm.nih.gov/pubmed/33368021
http://dx.doi.org/10.1007/s11739-020-02601-y
work_keys_str_mv AT levimarcel covid19coagulopathyisitdisseminatedintravascularcoagulation
AT ibatoshiaki covid19coagulopathyisitdisseminatedintravascularcoagulation

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