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Concurrent Genetic Alterations and Other Biomarkers Predict Treatment Efficacy of EGFR-TKIs in EGFR-Mutant Non-Small Cell Lung Cancer: A Review
Epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) greatly improve the survival and quality of life of non-small cell lung cancer (NSCLC) patients with EGFR mutations. However, many patients exhibit de novo or primary/early resistance. In addition, patients who initially respond...
Autores principales: | Guo, Yijia, Song, Jun, Wang, Yanru, Huang, Letian, Sun, Li, Zhao, Jianzhu, Zhang, Shuling, Jing, Wei, Ma, Jietao, Han, Chengbo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7758444/ https://www.ncbi.nlm.nih.gov/pubmed/33363040 http://dx.doi.org/10.3389/fonc.2020.610923 |
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