An innovative data analysis strategy for accurate next-generation sequencing detection of tumor mitochondrial DNA mutations

Next-generation sequencing technology has been commonly applied to detect mitochondrial DNA (mtDNA) mutations, which are reported to be strongly associated with cancers. However, several key challenges still exist regarding bioinformatics analysis of mtDNA sequencing data that greatly affect the det...

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Detalles Bibliográficos
Autores principales: Guo, Shanshan, Zhou, Kaixiang, Yuan, Qing, Su, Liping, Liu, Yang, Ji, Xiaoying, Gu, Xiwen, Guo, Xu, Xing, Jinliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7758456/
https://www.ncbi.nlm.nih.gov/pubmed/33376630
http://dx.doi.org/10.1016/j.omtn.2020.11.002

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