Cargando…
Quercetin Suppresses Apoptosis and Attenuates Intervertebral Disc Degeneration via the SIRT1-Autophagy Pathway
Intervertebral disc degeneration (IDD) has been generally accepted as the major cause of low back pain (LBP), which causes an enormous socioeconomic burden. Previous studies demonstrated that the apoptosis of nucleus pulposus (NP) cells and the dyshomeostasis of extracellular matrix (ECM) contribute...
Autores principales: | Wang, Dong, He, Xin, Wang, Di, Peng, Pandi, Xu, Xiaolong, Gao, Bo, Zheng, Chao, Wang, Han, Jia, Haoruo, Shang, Qiliang, Sun, Zhen, Luo, Zhuojing, Yang, Liu |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7758489/ https://www.ncbi.nlm.nih.gov/pubmed/33363176 http://dx.doi.org/10.3389/fcell.2020.613006 |
Ejemplares similares
-
Endoplasmic Reticulum Stress: An Emerging Therapeutic Target for Intervertebral Disc Degeneration
por: Wang, Dong, et al.
Publicado: (2022) -
SIRT5-related desuccinylation modification of AIFM1 protects against compression-induced intervertebral disc degeneration by regulating mitochondrial homeostasis
por: Mao, Jianxin, et al.
Publicado: (2023) -
Targeting clock-controlled gene Nrf2 ameliorates inflammation-induced intervertebral disc degeneration
por: Peng, Pandi, et al.
Publicado: (2022) -
Injectable hydrogel with nucleus pulposus-matched viscoelastic property prevents intervertebral disc degeneration
por: Jia, Haoruo, et al.
Publicado: (2022) -
Eicosapentaenoic Acid-Induced Autophagy Attenuates Intervertebral Disc Degeneration by Suppressing Endoplasmic Reticulum Stress, Extracellular Matrix Degradation, and Apoptosis
por: Lin, Zhen, et al.
Publicado: (2021)