iPSC-derived hepatocytes generated from NASH donors provide a valuable platform for disease modeling and drug discovery

Non-alcoholic fatty liver disease (NAFLD) affects 30–40% of adults and 10% of children in the US. About 20% of people with NAFLD develop non-alcoholic steatohepatitis (NASH), which may lead to cirrhosis and liver cancer, and is projected to be a leading cause of liver transplantation in the near fut...

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Detalles Bibliográficos
Autores principales: Gurevich, Igor, Burton, Sarah A., Munn, Christie, Ohshima, Makiko, Goedland, Madelyn E., Czysz, Katherine, Rajesh, Deepika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7758638/
https://www.ncbi.nlm.nih.gov/pubmed/33268331
http://dx.doi.org/10.1242/bio.055087

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7758638/
https://www.ncbi.nlm.nih.gov/pubmed/33268331
http://dx.doi.org/10.1242/bio.055087

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