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iPSC-derived hepatocytes generated from NASH donors provide a valuable platform for disease modeling and drug discovery
Non-alcoholic fatty liver disease (NAFLD) affects 30–40% of adults and 10% of children in the US. About 20% of people with NAFLD develop non-alcoholic steatohepatitis (NASH), which may lead to cirrhosis and liver cancer, and is projected to be a leading cause of liver transplantation in the near fut...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Company of Biologists Ltd
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7758638/ https://www.ncbi.nlm.nih.gov/pubmed/33268331 http://dx.doi.org/10.1242/bio.055087 |